Neoadjuvant stereotactic body radiation therapy with durvalumab and…
Combining radiation with two immunotherapy drugs significantly improved complete response rates in high-risk hormone-receptor-positive breast cancer, especially in tumors previously resistant to single immunotherapy.
- Lab
- Preclinical
- Early trials
- Late trials
- In practice
Neoadjuvant Paclitaxel, Trastuzumab, and Pertuzumab for Stage II to…
Abbreviated 12-week chemotherapy plus dual-targeted therapy achieved exceptional 5-year outcomes in HER2+ breast cancer, with blood tests potentially guiding safe treatment reduction.
Near-term implementable findingDeep learning-driven MRI radiomics reveals biological subtypes and…
Machine learning analysis of routine MRI scans identifies three distinct rectal cancer subtypes with different prognosis, improving prediction of who needs aggressive post-surgery treatment.
Early disease detection (neurodegenerative)Alpha-Synuclein Seed Amplification Assay in CSF, Skin, and…
A spinal fluid test detects Parkinson's disease pathology years before symptoms appear, opening possibilities for earlier intervention in at-risk individuals.
Early cancer detection or preventionCEMIP1 and TACSTD2 as circulating mRNA biomarkers for early detection…
Two blood-based markers detect colorectal cancer across its full spectrum from precancerous polyps to advanced disease, supporting development of simpler screening tests.