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‹ Mon · 23 Mar 2026
Promising but preliminary

Recent Advances in Nanoscale Sprayable Hydrogels for Cancer Management: Nanoparticle-Loaded Formulations for Therapy and Prevention

Sprayable hydrogels applied during cancer surgery show promise in preventing local tumor recurrence in preclinical studies.

This review categorizes sprayable hydrogel platforms by cancer type, mechanism, and therapeutic goal, documenting quantitative improvements in preclinical tumor suppression including over 80% reduction in local recurrence at surgical margins. Clinical translation remains constrained by technical and regulatory challenges, and no human trial data are included.

What the study was

Study design
Narrative review of preclinical literature
Population
Various cancer types (preclinical models; peritoneal carcinomatosis, skin tumors, mucosal lesions)
Category
Drug Development
Maturity
Exploratory
Journal
International Journal of Nanomedicine

Why it surfaced

Review of preclinical data only; no human data; low novelty versus existing literature. Useful for technology tracking but low triage priority.

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