Management and Outcome of Failed Transcatheter Tricuspid Edge-to-Edge Repair: Insights From the FATE International Registry
Device failures in tricuspid valve repair are rare, though outcomes remain challenging—signaling the need to refine which patients benefit most from this procedure.
In this international registry of 2,278 T-TEER procedures across 31 centers, device failure occurred in 5.4%, predominantly single-leaflet device attachment (75%). While reintervention reduced tricuspid regurgitation more effectively than medical management, clinical outcomes (death/HF hospitalization) remained similarly poor at ~38% at 8 months, highlighting the need for better patient selection and rescue strategies.
What the study was
- Study design
- Retrospective multicenter registry (31 centers, 2017–2024)
- Population
- Patients undergoing transcatheter tricuspid edge-to-edge repair (T-TEER), experienced device failure
- Sample size
- 2278
- Category
- Treatment Innovation
- Maturity
- Validated
- Journal
- JACC: Cardiovascular Interventions
Why it surfaced
Large multicenter registry (n=2,278) providing real-world data on T-TEER failure mechanisms and outcomes; clinically relevant for structural heart disease programs but outside core watchlist topics.
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