Associations of epigenetic age acceleration with motor impairment: Evidence from the Parkinson's Progression Markers Initiative cohort.
Biological aging clocks linked to movement problems in Parkinson's disease may help predict who will decline faster and need closer monitoring.
This study from the PPMI cohort demonstrates that epigenetic age acceleration is associated with motor impairment in Parkinson's disease. The finding links biological aging clocks to PD progression, potentially useful for prognosis and stratification.
What the study was
- Study design
- Cohort study
- Population
- Parkinson's disease cohort (PPMI)
- Category
- Diagnostics
- Maturity
- Exploratory
- Journal
- Neurobiology of Aging
Why it surfaced
Aging/epigenetics in neurodegeneration. Well-established cohort but incremental finding. Recovered from deferred PMIDs.
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