Increased CD103+ T lymphocytes in lymph nodes as a marker of metastasis from non-haematopoietic malignancies
A simple blood test marker identifies hidden cancer spread in lymph nodes with near-perfect accuracy, enabling earlier detection.
Elevated CD103+ T cells in lymph node flow cytometry can distinguish metastatic carcinoma from benign/lymphoma conditions with near-perfect specificity. This simple flow cytometry marker could serve as an early alert for occult solid tumor metastasis during routine lymph node workups.
What the study was
- Study design
- Retrospective diagnostic study
- Population
- Patients with clinically concerning lymphadenopathy
- Sample size
- 126
- Category
- Diagnostics
- Maturity
- Exploratory
- Journal
- Journal of Clinical Pathology
Why it surfaced
Novel diagnostic biomarker with excellent specificity; small sample needs prospective validation.
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