Multidimensional tumor heterogeneity and its role in therapeutic resistance.
Understanding why tumors become resistant to drugs through their internal diversity is essential to developing more effective combination therapies.
This review explores how tumors evade treatment through multiple dimensions of heterogeneity including spatial, temporal, and functional diversity. Understanding these mechanisms is crucial for developing strategies to overcome drug resistance.
What the study was
- Study design
- Review
- Category
- Genomics/Precision Medicine
- Maturity
- Exploratory
- Journal
- Frontiers in immunology
Why it surfaced
Broad review of tumor heterogeneity mechanisms. Conceptual rather than translational.
A plain-language summary of published research — not medical advice. Talk to a clinician about your own care.