Kallikrein related peptidases 7 and 10 and their substrate desmoglein 3 are upregulated in early stage pancreatic cancerous lesions.
Pancreatic cancer researchers have identified promising early warning markers that could eventually help catch this disease before symptoms appear.
Kallikrein-related peptidases 7 and 10 and their substrate desmoglein 3 are upregulated in early pancreatic cancer precursor lesions, potentially serving as novel early biomarker candidates. This is exploratory translational work from a Mayo Clinic-affiliated group addressing the major unmet need for early pancreatic cancer detection.
What the study was
- Study design
- Translational biomarker study (tissue analysis of early pancreatic lesions)
- Population
- Early-stage pancreatic cancerous lesion tissue samples
- Category
- Early Detection
- Maturity
- Exploratory
- Journal
- Scientific reports
Why it surfaced
Early pancreatic cancer biomarker candidates (KLK7/KLK10/DSG3) in tissue; high unmet need context, Sci Rep publication. Exploratory translational evidence only.
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