A Behavioral Intervention to Improve Symptoms After Hematopoietic Cell Transplantation
A brief behavioral program targeting sleep and activity after bone marrow transplant reduces fatigue and depression in these vulnerable patients.
This pilot RCT (n=39) demonstrated that a 3-session behavioral intervention targeting sleep and activity patterns post-hematopoietic cell transplantation was feasible, acceptable, and showed preliminary efficacy signals for fatigue, insomnia, and depression. Effect sizes warrant a fully powered trial of this scalable and low-cost intervention.
What the study was
- Study design
- Pilot randomized controlled trial (n=39, 89.7% completion)
- Population
- Patients recovering from hematopoietic cell transplantation
- Sample size
- 39
- Category
- Treatment Innovation
- Maturity
- Exploratory
- Journal
- Journal of Pain and Symptom Management
Why it surfaced
RCT design in an underserved symptom domain (post-HCT fatigue/insomnia) with high unmet need; pilot only but feasibility established; warrants a powered trial.
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