Temporal and demographic trends in infective gastroenteritis-related mortality among U.S. adults: A 25-year nationwide analysis (1999-2023)
Though gastroenteritis deaths fell after 2005, Native American and elderly populations still face disproportionate risk, guiding where prevention efforts matter most.
A 25-year CDC WONDER analysis of 304,378 gastroenteritis deaths in U.S. adults documented a sharp mortality rise 1999-2005 followed by decline, with persistent disparities across age, race, and geography. Adults ≥85 years bore the greatest mortality burden, and NH American Indian populations had the highest age-adjusted rates, highlighting unaddressed equity gaps in prevention.
What the study was
- Study design
- Nationwide population-based trend analysis (CDC WONDER, joinpoint regression)
- Population
- U.S. adults ≥25 years, stratified by sex, race/ethnicity, region, urbanization, age
- Sample size
- 304378
- Category
- Public Health
- Maturity
- Validated
- Journal
- Journal of the National Medical Association
Why it surfaced
Large-scale (304K deaths), 25-year nationwide data documenting mortality trends and persistent racial/age disparities; ≥85 population and NH American Indians disproportionately affected; provides actionable public health intelligence; strong design (nationwide CDC data + joinpoint regression).
A plain-language summary of published research — not medical advice. Talk to a clinician about your own care.