Association of socioeconomic status with intracranial arterial plaque: mediated by cardiometabolic risk factors
Low socioeconomic status links to more brain artery plaque primarily through blood pressure, suggesting targeted control could narrow disparities.
In 3065 Chinese adults, low socioeconomic status was significantly associated with increased intracranial atherosclerotic plaque burden, with systolic blood pressure as the dominant mediator (23-30%). These findings underscore the importance of cardiometabolic risk factor control in low-SES populations as a pathway to reduce disparities in cerebrovascular disease.
What the study was
- Study design
- Cross-sectional mediation analysis
- Population
- Chinese adults from PRECISE study baseline (mean age 61.2)
- Sample size
- 3065
- Category
- Public Health
- Maturity
- Exploratory
- Journal
- Stroke and Vascular Neurology
Why it surfaced
n=3065; mediation analysis identifies SBP as dominant mediator of SES-intracranial plaque relationship; directly relevant to health equity and cardiometabolic prevention.
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