Tumor-infiltrating lymphocytes in triple-negative breast cancer: molecular mechanisms, spatial regulation, and therapeutic implications
Understanding immune cells and fibroblasts in triple-negative breast cancer reveals new targets for improving immunotherapy response.
This review characterizes TIL biology in triple-negative breast cancer, focusing on CAF interactions, spatial regulatory mechanisms, and therapeutic implications for immunotherapy. The synthesis highlights emerging targets for improving immunotherapy response rates in TNBC.
What the study was
- Study design
- Narrative review
- Population
- TNBC patients
- Category
- Treatment Innovation
- Maturity
- Exploratory
- Journal
- Breast Cancer Research
Why it surfaced
TNBC immunotherapy context review; relevant for watchlist tracking of novel therapeutics in breast cancer.
A plain-language summary of published research — not medical advice. Talk to a clinician about your own care.