Pulse pressure associates with severity and worse outcomes in patients with stable coronary artery disease
A simple pulse pressure measurement predicts heart attack and stroke risk better than standard blood pressure readings in coronary disease patients.
This large prospective cohort of 7,027 stable CAD patients demonstrates that pulse pressure is a superior independent predictor of stroke and combined cardiovascular outcomes compared to systolic blood pressure alone, after adjusting for confounders over 36.4 months. Pulse pressure correlates with disease severity (Gensini Score) and 3-vessel disease burden, supporting its use as a clinically accessible cardiometabolic risk stratification tool.
What the study was
- Study design
- Prospective cohort study with multivariate Cox regression
- Population
- Patients with stable coronary artery disease and normal ejection fraction, Fuwai Hospital, China
- Sample size
- 7027
- Category
- Diagnostics
- Maturity
- Validated
- Journal
- npj Cardiovascular Health
Why it surfaced
Large prospective cohort (N=7,027) with long follow-up demonstrating pulse pressure as an independent CV risk predictor; PP is a routinely measured, zero-cost clinical parameter. Fuwai Hospital, China (national cardiovascular center).
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