Non-infectious fever defines a subgroup of patients with poorer survival outcomes in high-risk myelodysplastic syndrome
Unexplained fever in high-risk patients with myelodysplastic syndrome identifies a worse-prognosis group using only clinical observation.
This multi-institutional retrospective Japanese cohort demonstrates that non-infectious fever in high-risk MDS defines a clinically relevant poor-prognosis subgroup, providing a new clinical feature for risk stratification that is readily assessable at diagnosis without additional testing. Sample size not available from abstract alone — classification confidence reduced accordingly.
What the study was
- Study design
- Multi-institutional retrospective cohort (9 institutions, Kyoto prefecture)
- Population
- High-risk MDS patients at 9 Japanese institutions
- Category
- Diagnostics
- Maturity
- Exploratory
- Journal
- British Journal of Haematology
Why it surfaced
Practical clinical prognostic biomarker (non-infectious fever) in high-risk MDS from multi-institutional Japanese data. Published in Br J Haematol. Sample size not retrievable from abstract — downgraded one confidence level.
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