Taxonomic and functional remodeling of the gut microbiota during aging and implications for microbiota-derived biomarkers
Consistent age-related gut microbiota patterns identified across populations suggest reproducible aging biomarkers and intervention targets.
This review synthesizes evidence on age-associated gut microbiota changes, identifying conserved taxonomic and functional patterns across multiple aging and disease conditions. The integration of metagenomic and metabolomic approaches provides a framework for identifying reproducible microbiome-based aging biomarkers, complementary to the Akkermansia RCT finding in this run.
What the study was
- Study design
- Narrative review
- Population
- General aging human population (review synthesis)
- Category
- Diagnostics
- Maturity
- Exploratory
- Journal
- World Journal of Microbiology and Biotechnology
Why it surfaced
Relevant aging-microbiota review. Design quality 0 (review). Provides context for interpreting Akkermansia A. muciniphila RCT (TR-2026-05-13-005) results.
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