Single-cell impedance sensing on integrated circuit chip for fast tumor diagnosis
An inexpensive lab-on-chip diagnoses tumors during surgery in 20 minutes, potentially improving surgical decision-making in the operating room.
An integrated-circuit-based single-cell electric cell-substrate impedance sensing (IC-ECIS) chip fabricated at under $1/chip provides intraoperative tumor diagnosis in 20 minutes across 6 tissue types, validated against histopathology. The low cost and rapid turnaround represent a potentially transformative point-of-care approach for intraoperative surgical decision-making.
What the study was
- Study design
- Device development and clinical sample validation
- Population
- Clinical tumor specimens from thyroid, liver, gallbladder, bile duct, breast, and pancreas
- Category
- Diagnostics
- Maturity
- Exploratory
- Journal
- Microsystems & Nanoengineering
Why it surfaced
Novel $1/chip intraoperative diagnostic platform with 20-minute turnaround. Sample size and validation set size not disclosed in abstract. Feasibility stage.
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