Time-Dependent Association Between Prehospital Blood Pressure and Outcomes in Acute Spontaneous Intracerebral Hemorrhage
Blood pressure matters more for brain hemorrhage survival when patients reach the hospital slowly, suggesting EMS guidelines should account for arrival time.
This registry-based study of 690 ICH patients demonstrates that elevated prehospital blood pressure predicts in-hospital mortality only when onset-to-arrival time exceeds 3 hours, suggesting that BP management thresholds should be contextualized by time-to-hospital arrival in prehospital ICH protocols. These findings have potential implications for EMS-initiated BP targets in spontaneous ICH.
What the study was
- Study design
- Retrospective cohort study using prospectively maintained stroke registry
- Population
- Adults ≥18y with spontaneous ICH transported by EMS within 24h, tertiary center Taipei, 2016-2022; n=690 (336 early <3h, 354 late ≥3h)
- Sample size
- 690
- Category
- Diagnostics
- Maturity
- Validated
- Journal
- European Journal of Neurology
Why it surfaced
Clinically relevant time-stratified analysis of prehospital BP in ICH; novel nuance for EMS protocol design. Large registry, rigorous multivariable adjustment and RCS analysis.
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