Diagnostic performance of urinary tumor DNA in urothelial carcinoma: A systematic review and network meta-analysis.
Non-invasive urine tests for tumor DNA could catch bladder cancers earlier, sparing some patients from uncomfortable tissue biopsies while improving detection accuracy.
This systematic review and network meta-analysis evaluates the diagnostic accuracy of urinary tumor DNA across multiple assays for urothelial carcinoma detection. It provides a comprehensive evidence base for non-invasive liquid biopsy diagnostics in bladder/upper tract cancers, a clinically important early-detection application.
What the study was
- Study design
- Systematic review and network meta-analysis
- Population
- Patients with urothelial carcinoma undergoing urinary tumor DNA testing
- Category
- Early Detection
- Maturity
- Validated
- Journal
- Urologic Oncology
Why it surfaced
Network meta-analysis of urinary tumor DNA for non-invasive urothelial cancer detection — directly on early-detection watchlist, strong design quality, clinical translation potential.
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