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‹ Wed · 3 Jun 2026
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Acquired hemophilia A following influenza vaccination: a case report and literature review

A rare case suggests flu vaccination may rarely trigger a bleeding disorder, warranting consideration in diagnosis of unexplained bleeding.

An 81-year-old man developed acquired hemophilia A following influenza vaccination, successfully treated with hemostatic therapy and immunosuppressants. This rare case suggests influenza vaccination as a possible trigger for AHA and should be considered in the differential diagnosis of newly diagnosed AHA without other identifiable causes.

What the study was

Study design
Case report with literature review
Population
Single patient: 81-year-old male with AHA after influenza vaccination
Sample size
1
Category
Diagnostics
Maturity
Exploratory
Journal
Annals of Hematology

Why it surfaced

Single case report of AHA trigger. Conservative scoring cap applied (single case: max score 4). Limited evidentiary value; excluded from further pipeline processing.

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