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‹ Thu · 4 Jun 2026
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Targeted Supplementation and Nutritional Strategies for Healthy Aging: A Review of Physiological and Molecular Benefits

Protein and mitochondrial-support supplements consistently improve muscle and cell energy in aging studies, though longer trials are needed before widespread recommendations.

This narrative review synthesizes evidence from 32 human studies on nutritional compounds targeting aging pathways, finding consistent support for protein/collagen supplementation for muscle mass and emerging evidence for mitochondrial-support compounds (NAD+ precursors, glycine+NAC). Evidence is predominantly short-term and heterogeneous — longer trials needed before clinical recommendations.

What the study was

Study design
Narrative review (32 human studies)
Population
Older adults
Category
Prevention
Maturity
Exploratory
Journal
Curr Nutr Rep

Why it surfaced

T8 catch for aging/longevity topic. Narrative review — no new primary data. Relevant background for aging-supplement pipeline context.

A plain-language summary of published research — not medical advice. Talk to a clinician about your own care.