Chromoanagenesis in Myelodysplastic Syndromes Is Associated With…
Optical genome mapping identifies a rare, ultra-high-risk subset of blood cancers with severe genetic chaos, enabling earlier recognition of patients needing urgent intervention.
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Efficacy and safety of pyrimidine nucleos(t)ide therapy in thymidine…
A new pill doubles survival time for children with a rare mitochondrial disease that previously had no effective treatment, with measurable improvements in walking and movement.
Near-term implementable findingDeciphering elevated risk of life-threatening hemorrhage and early…
A blood test pinpoints which leukemia patients face life-threatening bleeding, allowing doctors to adjust treatment doses upfront and improve survival in this vulnerable group.
Near-term implementable findingThe impact of IPI risk factors on CAR T-cell therapy or allogeneic…
CAR-T cell therapy dramatically reduces treatment-related deaths compared to stem cell transplant in patients with aggressive lymphoma, though high-risk patients may benefit from earlier transplant planning.
Novel or significantly improved treatmentA multicenter randomized phase II/III trial of salvage treatment for…
A new trial tests whether a daily pill can match radiation therapy's effectiveness against brain lymphoma while sparing patients from severe long-term memory and thinking problems.