Liver-related autoantibodies in Wilson disease: increased prevalence and unclear clinical significance.

Autoimmune markers appear unexpectedly high in Wilson disease, raising awareness of diagnostic overlap with autoimmune liver disease.

Liver-related autoantibodies (ANA, SMA, anti-LKM1) show increased prevalence in Wilson disease compared to healthy controls, highlighting potential overlap with autoimmune hepatitis that may complicate diagnosis and management of this rare genetic copper metabolism disorder.

What the study was

Study design

retrospective_cohort

Category

rare_diseases

Maturity

clinical

Journal

Advances in Medical Sciences

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