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‹ Mon · 29 Jun 2026
Underserved or high-risk populations

Real-World Evidence of the Effectiveness and Safety of Biosynthetic Semaglutide in Type 2 Diabetes: A Multicentre Study From Pakistan.

Affordable biosynthetic semaglutide works as well as brand-name versions for blood sugar and weight loss, expanding diabetes treatment access in lower-income regions.

Biosynthetic semaglutide shows comparable real-world glycemic and weight loss effectiveness to branded semaglutide in a Pakistani multicentre setting, demonstrating access-expanded GLP-1 therapy in a high-burden T2DM region. LMIC-specific evidence is critical for expanding affordable GLP-1 access.

What the study was

Study design
Prospective multicentre observational cohort
Population
T2DM patients in Pakistan; n=217; 30-week follow-up; multicenter
Sample size
217
Category
Treatment Innovation
Maturity
Validated
Journal
Diabetes, obesity & metabolism

Why it surfaced

First real-world multicentre biosynthetic semaglutide data in LMIC; addresses access gap; n=217 limits statistical power.

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