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‹ Wed · 1 Jul 2026
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Frailty and Cognitive Impairment in Chronic Kidney Disease: A Systematic Review and Meta-Analysis.

Kidney disease patients with frailty face steeper cognitive decline, suggesting need for earlier cognitive screening in this population.

This SR+MA demonstrates a robust association between frailty and cognitive decline in chronic kidney disease, quantifying the excess risk and identifying patient characteristics that amplify cognitive vulnerability in this already-compromised population. The findings support routine frailty and cognitive screening in CKD care, with implications for treatment planning, dialysis decisions, and transplant candidacy evaluation.

What the study was

Study design
Systematic review and meta-analysis
Category
Diagnostics
Maturity
Validated
Journal
J Nurs Scholarsh

Why it surfaced

SR+MA design; high prevalence of frailty-CKD-cognitive triad in aging populations; direct clinical management implications for a large patient group; nursing scholarship journal with broad clinical readership.

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