A comprehensive urine workflow enables robust methylation and fragmentation analysis of cell-free DNA.
Urine cell-free DNA testing now enables non-invasive cancer monitoring through a fully validated workflow.
This Sci Rep study from Heitzer and Deleuze labs presents a validated workflow for urine cell-free DNA isolation enabling both methylation profiling and fragmentation analysis from urine samples. The workflow expands liquid biopsy capabilities to this fully non-invasive source with particular relevance for urological cancer surveillance and broad cancer monitoring.
What the study was
- Study design
- Method development and validation study
- Population
- Patients providing urine samples for non-invasive cfDNA analysis
- Category
- Diagnostics
- Maturity
- Validated
- Journal
- Scientific reports
Why it surfaced
Sci Rep; urine cfDNA workflow for methylation+fragmentation by Heitzer (leading cfDNA group) and Deleuze (CEA/CNG); enables non-invasive monitoring expansion.
A plain-language summary of published research — not medical advice. Talk to a clinician about your own care.