Impact of doublet post-transplant maintenance on outcomes in multiple myeloma: a propensity score-matched analysis.
Using two maintenance drugs after stem cell transplant improves survival in multiple myeloma compared to single-agent therapy.
This propensity score-matched analysis compared doublet versus single-agent post-transplant maintenance in multiple myeloma using real-world data from a major academic center network. Doublet maintenance showed superior survival outcomes, providing practical evidence for intensification of post-transplant maintenance in eligible MM patients.
What the study was
- Study design
- Retrospective cohort with propensity score matching
- Population
- Multiple myeloma patients post-autologous stem cell transplant
- Category
- Treatment Innovation
- Maturity
- Validated
- Journal
- Bone marrow transplantation
Why it surfaced
Bone Marrow Transplantation; real-world propensity-matched analysis of doublet MM maintenance; near-term practice guidance for post-transplant MM management.
A plain-language summary of published research — not medical advice. Talk to a clinician about your own care.