Triglyceride/HDL-cholesterol ratio as a predictor for treatment-related severe hypertriglyceridemia in children with lymphoid malignancies.
Simple baseline cholesterol ratio predicts severe treatment-side-effect risk in children, enabling early monitoring and preventive dietary strategies.
Malecka et al. retrospectively evaluated the pre-treatment triglyceride-to-HDL-cholesterol ratio as a predictor of severe treatment-related hypertriglyceridaemia during chemotherapy in paediatric patients with lymphoid malignancies in Scientific Reports. Early identification of high-risk patients using this simple baseline lipid ratio could prompt prophylactic monitoring and dietary interventions to reduce chemotherapy-related cardiovascular toxicity in children.
What the study was
- Study design
- Retrospective cohort study
- Population
- Paediatric patients with lymphoid malignancies undergoing chemotherapy
- Category
- Diagnostics
- Maturity
- Exploratory
- Journal
- Sci Rep
Why it surfaced
Novel lipid biomarker for predicting chemotherapy toxicity in paediatric lymphoid malignancies; open-access Sci Rep; relevant to T1 hematologic malignancy treatment safety.
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