Exercise-induced change in FGF21 and adiponectin and their association with metabolic syndrome in older women: a randomized controlled trial
Exercise raises protective hormones linked to healthier metabolism in aging women, supporting physical activity as a natural way to prevent metabolic disease.
A randomized controlled trial demonstrated that regular exercise in older women significantly elevated circulating FGF21 and adiponectin levels, with these biomarkers independently associated with lower prevalence of metabolic syndrome components. The findings support exercise as a modulator of FGF21/adiponectin signaling in aging populations with implications for preventive strategies targeting the cardiometabolic-aging intersection.
What the study was
- Study design
- Randomized controlled trial of exercise intervention in older women with metabolic syndrome assessment
- Population
- Older women with or at risk for metabolic syndrome
- Category
- Prevention
- Maturity
- Validated
- Journal
- J Nutr Health Aging
Why it surfaced
RCT demonstrating exercise-induced FGF21/adiponectin increases linked to metabolic syndrome improvement in older women; RCT design in aging population is high-quality evidence for aging/longevity watchlist.
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