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‹ Thu · 16 Jul 2026
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Pulmonary Alveolar Proteinosis in Greece-Turkiye-Cyprus: Answers in a Real-Life Comparison.

Inhaled medication alone works as well as invasive lung cleaning for a rare lung disease, avoiding hospitalization for some patients.

Inhaled GM-CSF alone shows comparable efficacy to whole lung lavage (WLL) or combined WLL+iGM-CSF in autoimmune PAP; pulmonary fibrosis development predicts treatment non-response across all therapy groups. This record was retained from the prior triage attempt for PubMed pipeline handoff.

What the study was

Study design
retrospective multicenter real-world study (n=130, 20-year follow-up)
Category
rare_diseases
Maturity
Validated
Journal
Respirology

Why it surfaced

Largest reported real-world multicenter cohort for PAP providing evidence that iGM-CSF alone is effective, potentially sparing patients from invasive WLL procedures in this rare disease.

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