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‹ Wed · 22 Jul 2026
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Advancement of subtype-based early breast cancer systematic therapy

Molecular subtype-guided therapy—combining targeted drugs and immunotherapy—transforms early breast cancer treatment options.

This review comprehensively covers advances in systemic therapy for early breast cancer organized by molecular subtype, highlighting how targeted agents, immunotherapy, and combinatorial strategies have transformed treatment options. The article synthesizes recent trial results and translates them into practical treatment considerations for early breast cancer management.

What the study was

Study design
Narrative review
Population
Early-stage breast cancer patients across HR+/HER2-, HER2+, and TNBC molecular subtypes
Category
Treatment Innovation
Maturity
Validated
Journal
Zhonghua yi xue za zhi

Why it surfaced

Comprehensive subtype-based early breast cancer systemic therapy review; useful for pipeline context on standard-of-care landscape in a high-volume disease.

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