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‹ Fri · 24 Jul 2026
Promising but preliminary

Effects of cow placenta extract on cognitive function in aged dogs: a randomized controlled trial.

Cow placenta extract improved cognitive function and reduced oxidative stress in aging dogs, suggesting potential for cognitive decline management.

BACKGROUND: Cow placenta extract (CPE) has demonstrated beneficial effects in antiaging; however, its effect on age-related cognitive decline remains unclear. CONCLUSIONS AND CLINICAL IMPORTANCE: A six-month CPE administration improved cognitive function and oxidative stress in aged dogs, suggesting its potential for long-term management of cognitive impairment.

What the study was

Study design
Randomized study
Sample size
45
Category
Public Health
Maturity
Exploratory
Journal
Journal of veterinary internal medicine

Why it surfaced

Score 5/10 (capped from 6): Randomized controlled trial in aged dogs — non-human study cap applied (max 5 for animal model). Species corrected to 'animal'. Components — novelty:1/3, relevance:1/3, design:2/2, population:1/2. Confidence: medium. Conservative scoring per v1.3 rubric.

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