Lymphocyte-derived microRNA hsa-miR-150-5p as a marker of inflammation-related kidney function impairment in the general population.
A specific microRNA marker linked to kidney disease could help identify at-risk patients earlier for preventive intervention.
Previous studies have demonstrated strong links between circulating microRNAs (miRNA), lymphocytes, and immune markers suggesting that miRNAs are key regulators of immune function and immune related diseases. Beyond this, miR-150-5p showed significant associations with kidney disease and also with several clinical markers of renal function.
What the study was
- Study design
- Cohort study
- Sample size
- 804
- Category
- Prevention
- Maturity
- Exploratory
- Journal
- Clinical immunology (Orlando, Fla.)
Why it surfaced
Score 5/10 [PROMISING_PRELIMINARY]: Cohort study (Journal Article) matched 'Cardiovascular-metabolic: GLP-1, SGLT2, '. Components — novelty:1/3, relevance:1/3, design:1/2, population:2/2. Confidence: high. Conservative scoring applied per v1.3 rubric.
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