Extracellular Vesicles in Cancer: Biomarkers, Mechanisms, and Emerging Diagnostic Technologies.
Extracellular vesicles emerge as a liquid biopsy source complementary to existing tests, potentially improving early cancer detection.
This review in Advanced Healthcare Materials synthesizes current knowledge on extracellular vesicles as cancer biomarkers, covering mechanisms of EV biogenesis in cancer, molecular cargo, and emerging EV-based diagnostic platforms for early detection. It positions EVs as a next-generation liquid biopsy source complementary to cfDNA and CTCs, cataloguing diagnostic technologies approaching clinical translation.
What the study was
- Study design
- Systematic review
- Population
- Cancer patients and preclinical models for EV-based diagnostics
- Category
- Early Detection
- Maturity
- Exploratory
- Journal
- Advanced healthcare materials
Why it surfaced
EV-based liquid biopsy is a rapidly developing field directly relevant to the T3 early cancer detection watchlist. Published in Advanced Healthcare Materials, a high-impact biomedical engineering journal. EARLY_CANCER_DETECTION flag applied.
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