Haematological pre-staging of colorectal cancer: Longitudinal trends identify high-risk metastatic phenotypes 24 months prior to diagnosis.
Routine blood test patterns detected up to two years before colorectal cancer diagnosis could flag high-risk patients for earlier screening and intervention.
Routine CBC parameters exhibit distinctive longitudinal trend signatures up to 24 months before colorectal cancer diagnosis, identifying high-risk metastatic phenotypes through temporal haematological patterns — demonstrating that routine blood tests may flag future CRC risk long before clinical presentation. This record was retained from the prior triage attempt for PubMed pipeline handoff.
What the study was
- Study design
- retrospective longitudinal cohort study
- Category
- cbc_ml_hematology
- Maturity
- Validated
- Journal
- Transl Oncol
Why it surfaced
First demonstration of CBC longitudinal trends predicting colorectal cancer 24 months prior to diagnosis — directly relevant to CBC/ML hematology watchlist and early cancer detection. Translational Oncology publication; could underpin CBC-based population cancer surveillance tools if externally validated.
A plain-language summary of published research — not medical advice. Talk to a clinician about your own care.