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39 papers read · 39 surfaced · 5 stood out
Today's lead · aging_longevity
Single-cell analysis of the progeria arterial wall reveals…
Detailed mapping of progeria's arterial damage reveals aging patterns that could help researchers understand how blood vessels age normally.
Merino LG, Revêchon G, Subhash S et al. · Genome Med
9/10
Impact score
Time to impact (est.)
- Lab
- Preclinical
- Early trials
- Late trials
- In practice
Promising but preliminary
Targeting ACSF2 overcomes Ara-C resistance in acute myeloid leukemia…
Blocking a specific protein restores chemotherapy sensitivity in treatment-resistant leukemia, opening a potential path forward for patients who've exhausted standard options.
Promising but preliminaryLow-dose bevacizumab plus atezolizumab enhances transarterial…
Adding two targeted drugs to a liver cancer procedure reduces immune suppression and improves survival outcomes in early patient data.
Promising but preliminaryEnhanced acetate uptake and metabolism in endothelial cells promote…
Blocking a metabolic pathway in tumor blood vessels enhances immunotherapy effectiveness against liver cancer in laboratory models.
Promising but preliminaryd-serine as a metabolic immune checkpoint in the tumour microenvironment.
A naturally occurring molecule controls immune suppression in gut tumors, offering a fresh therapeutic target grounded in the microenvironment.