The Role of Gut Microbiota Interventions in the Management of Frailty Syndrome: A Scoping Review and Bibliometric Analysis.
Gut-targeted interventions show emerging promise for reducing frailty severity and improving function in older adults, with this evidence base growing rapidly.
This nine-database scoping review synthesizes the emerging evidence for gut microbiota-targeted interventions (probiotics, prebiotics, synbiotics, FMT) in frailty syndrome, covering outcomes from frailty severity and physical function to microbiota composition and inflammatory markers across 4–26 weeks of intervention. Bibliometric analysis of 358 publications reveals exponential growth since 2016, highlighting this as a rapidly maturing evidence base warranting standardized clinical trials.
What the study was
- Study design
- scoping_review
- Category
- aging_longevity_population_health
- Maturity
- Validated
- Journal
- Geriatr Gerontol Int
Why it surfaced
Frailty is a major modifiable aging syndrome affecting millions of older adults; gut microbiota interventions represent an accessible and scalable therapeutic avenue; scoping synthesis useful for pipeline prioritization.
A plain-language summary of published research — not medical advice. Talk to a clinician about your own care.