Lipoprotein(a) and risk of subsequent Stanford type A aortic dissection in patients with acute coronary syndrome: a multicenter case-control study with Mendelian randomization analysis.
Lipoprotein(a) [Lp(a)] is associated with cardiovascular risk, but its role in Stanford type A aortic dissection (AD) following acute coronary syndrome (ACS) remains unclear. We evaluated whether Lp(a) at ACS presentation predicts subsequent type A AD, its incremental value, and to assess potential causal effects using a complementary two-sample Mendelian randomization (MR) analysis.
Lipoprotein(a) [Lp(a)] is associated with cardiovascular risk, but its role in Stanford type A aortic dissection (AD) following acute coronary syndrome (ACS) remains unclear. We evaluated whether Lp(a) at ACS presentation predicts subsequent type A AD, its incremental value, and to assess potential causal effects using a complementary two-sample Mendelian randomization (MR) analysis.
What the study was
- Study design
- Cohort/Observational Study
- Category
- Diagnostics
- Maturity
- Validated
- Journal
- Nutr Metab Cardiovasc Dis
Why it surfaced
Matched watchlist topic 'Cardiovascular-metabolic: GLP-1, SGLT2, cardiometabolic risk'. Study design: Cohort/Observational Study. Score: 8/10 (N:2, R:3, D:1, P:2).
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