📅 PUBMED DAILY TRIAGE — 2026-08-25 Window: 2026-08-24T09:18:25Z → 2026-08-25T09:18:25Z (CRDT) Topics scanned: 10 | Articles reviewed: 38 | Candidates evaluated: 118 High priority: 9 | Standard: 29 | Low/archive: 0 | Unsolicited finds: 5 Run status: SUCCESS
🔴🟠 HIGH PRIORITY (8+) — Best Finds by Topic
Hematologic malignancies (AML, MDS, CLL, MPN, lymphoma)
No high-priority finds today (best candidate scored 7/10).
CBC-based diagnostics and machine learning in hematology
No high-priority finds today (best candidate scored 5/10).
Early cancer detection (liquid biopsy, ctDNA, cfDNA)
PMID:42635240 · Large-scale simulation of coverage and error rate tradeoffs for cancer detection in cell-free DNA whole-genome sequencing. · 7/10 · Conservative triage based on the PubMed abstract, observational study, clinical relevance, and unmet-need signals. PMID:42635246 · Liquid biopsies reveal dual compartments of cancer risk from tumor and host-derived mutations. · 7/10 · Conservative triage based on the PubMed abstract, observational study, clinical relevance, and unmet-need signals. PMID:42635710 · Liquid biopsy in colorectal cancer: redefining surgical decision-making. · 7/10 · Conservative triage based on the PubMed abstract, narrative review, clinical relevance, and unmet-need signals. PMID:42635711 · Role of liquid biopsy in the multimodal assessment and treatment of esophageal cancer: a surgical perspective. · 7/10 · Conservative triage based on the PubMed abstract, observational study, clinical relevance, and unmet-need signals. PMID:42635847 · Minimal Residual Disease in Head and Neck Cancer: Molecular Surveillance and Clinical Action. · 7/10 · Conservative triage based on the PubMed abstract, validation study, clinical relevance, and unmet-need signals.
AI/ML in clinical diagnostics and imaging
PMID:42636163 · Artificial intelligence applications in radiology: the new frontier in interstitial lung diseases. · 6/10 · Conservative triage based on the PubMed abstract, validation study, clinical relevance, and unmet-need signals. PMID:42636552 · Research trends and evidence landscape of metabolomics and machine learning in the diagnosis of subclinical ketosis in dairy cows: a systematic review and bibliometric analysis. · 6/10 · Conservative triage based on the PubMed abstract, systematic review, clinical relevance, and unmet-need signals.
Precision oncology and genomic medicine
PMID:42634729 · Precision Diagnostics in Age-Related Hearing Loss: Emerging Molecular Biomarkers for Early Detection and Targeted Prevention. · 6/10 · Conservative triage based on the PubMed abstract, validation study, clinical relevance, and unmet-need signals.
Novel therapeutics: immunotherapy, CAR-T, targeted therapy
No high-priority finds today (best candidate scored 7/10).
Cardiovascular-metabolic: GLP-1, SGLT2, cardiometabolic risk
PMID:42636272 · Exploring The Role of GLP-1 Receptor Agonists and DPP4 Inhibitors in the Treatment of Opioid Use Disorder: A Scoping Review. · 7/10 · Conservative triage based on the PubMed abstract, randomized controlled trial, clinical relevance, and unmet-need signals.
Aging, longevity, and population health
No high-priority finds today (best candidate scored 5/10).
Rare diseases with high unmet need
No high-priority finds today (best candidate scored 7/10).
🟢⚪ STANDARD (5-7) — Top by Topic
Hematologic malignancies (AML, MDS, CLL, MPN, lymphoma)
PMID:42636977 · Sustained benefit of adjuvant olaparib in women with germline BRCA1- and BRCA2- -associated high-risk HER2-negative early breast cancer: Updated results from the OlympiA phase III trial. · 7/10 · Treatment Innovation PMID:42636737 · Therapeutic bronchoscopy for pulmonary lymphoma: data from the EpiGETIF registry. · 6/10 · Treatment Innovation PMID:42637611 · Targeting the Menin-KMT2A Axis in AML: Translating Molecular Insights into Therapeutic Success. · 6/10 · Treatment Innovation PMID:42637369 · Disrupting the cardiolipin oxidation-apoptosis axis: low-temperature, high-salinity depuration extends anhydrous storage in Pacific oysters. · 5/10 · Other PMID:42637517 · Single-cell chromatin profiling reveals relapse-related priming in pediatric acute myeloid leukemia. · 5/10 · Treatment Innovation
CBC-based diagnostics and machine learning in hematology
PMID:42636993 · Integrating CBC-derived Inflammatory Biomarkers with Machine Learning for Discriminating Stable and Exacerbated COPD. · 5/10 · Diagnostics
Early cancer detection (liquid biopsy, ctDNA, cfDNA)
PMID:42635240 · Large-scale simulation of coverage and error rate tradeoffs for cancer detection in cell-free DNA whole-genome sequencing. · 7/10 · Early Detection PMID:42635246 · Liquid biopsies reveal dual compartments of cancer risk from tumor and host-derived mutations. · 7/10 · Early Detection PMID:42635710 · Liquid biopsy in colorectal cancer: redefining surgical decision-making. · 7/10 · Early Detection PMID:42635711 · Role of liquid biopsy in the multimodal assessment and treatment of esophageal cancer: a surgical perspective. · 7/10 · Early Detection PMID:42635847 · Minimal Residual Disease in Head and Neck Cancer: Molecular Surveillance and Clinical Action. · 7/10 · Early Detection
AI/ML in clinical diagnostics and imaging
PMID:42636163 · Artificial intelligence applications in radiology: the new frontier in interstitial lung diseases. · 6/10 · Early Detection PMID:42636552 · Research trends and evidence landscape of metabolomics and machine learning in the diagnosis of subclinical ketosis in dairy cows: a systematic review and bibliometric analysis. · 6/10 · Early Detection PMID:42636698 · Comparing individual and peer-supported ChatGPT use in nursing case analysis: Effects on nursing diagnostic skills and cognitive load in a randomized controlled trial. · 6/10 · Treatment Innovation PMID:42637179 · Integrating multimodality CT-MRI deep learning with clinical-radiological features for preoperative hepatocellular carcinoma grading: a multicenter study. · 5/10 · Diagnostics PMID:42637678 · Merging artificial intelligence and retinal vascular geometric parameters: A novel tool for diagnosis and prognosis prediction of diabetic nephropathy. · 5/10 · Diagnostics
Precision oncology and genomic medicine
PMID:42634729 · Precision Diagnostics in Age-Related Hearing Loss: Emerging Molecular Biomarkers for Early Detection and Targeted Prevention. · 6/10 · Early Detection PMID:42636717 · Rethinking and advancing meta-analyses and randomized trials of psychotherapies. · 6/10 · Treatment Innovation PMID:42636817 · [Cholangiocarcinoma as a model disease: new pathways in personalized medicine]. · 5/10 · Treatment Innovation PMID:42636890 · Living drug carriers: Microbial and bioengineered platforms redefining precision therapeutic and immunomodulatory delivery. · 5/10 · Genomics/Precision Medicine PMID:42637140 · Artificial intelligence (AI)-enabled platforms for cancer vaccine engineering. · 5/10 · Diagnostics
Novel therapeutics: immunotherapy, CAR-T, targeted therapy
PMID:42636656 · B cells in nasopharyngeal carcinoma: From prognostic signal to therapeutic hypothesis-A critical appraisal of the RATIONALE-309 biomarker analysis. · 7/10 · Treatment Innovation PMID:42637010 · Radiologic, Pathologic, and Deep Learning Predictors of Response to Immune Checkpoint Blockade in Renal Cell Carcinoma Patients Undergoing Post-Treatment Nephrectomy. · 6/10 · Treatment Innovation PMID:42636674 · Consensus subtypes and a generalizable prognostic signature defined by an R-loop score in hepatocellular carcinoma: Multi-omics analyses pinpoint KIF2A-positive proliferative tumor cells. · 5/10 · Treatment Innovation PMID:42636898 · Killing to cure: harnessing poxvirus-driven cell death for viral immunotherapy. · 5/10 · Treatment Innovation PMID:42637140 · Artificial intelligence (AI)-enabled platforms for cancer vaccine engineering. · 5/10 · Diagnostics
Cardiovascular-metabolic: GLP-1, SGLT2, cardiometabolic risk
PMID:42636272 · Exploring The Role of GLP-1 Receptor Agonists and DPP4 Inhibitors in the Treatment of Opioid Use Disorder: A Scoping Review. · 7/10 · Treatment Innovation PMID:42636218 · Antidiabetic medications and risk of cognitive disorders in type 2 diabetes: A retrospective cohort study. · 5/10 · Treatment Innovation PMID:42637139 · GLP-1 receptor agonists and ocular disease: Therapeutic promise, mechanistic insights and emerging safety signals. · 5/10 · Other
Aging, longevity, and population health
PMID:42634650 · Predictive Value of Biological Age for All-Cause Mortality in Patients with COPD. · 5/10 · Public Health
Rare diseases with high unmet need
PMID:42637650 · Metaplastic breast cancer: A single-centre retrospective experience. · 7/10 · Treatment Innovation PMID:42636737 · Therapeutic bronchoscopy for pulmonary lymphoma: data from the EpiGETIF registry. · 6/10 · Treatment Innovation PMID:42635583 · Evaluating deucrictibant for the treatment of hereditary angioedema. · 5/10 · Treatment Innovation PMID:42636416 · Long-Term Outcomes in Autoimmune Encephalitis: A Nationwide, Clinical Study in Denmark. · 5/10 · Early Detection PMID:42636490 · Sacral extradural arteriovenous fistula in a filum terminale lipoma with retained medullary cord: illustrative case. · 5/10 · Treatment Innovation
💡 UNSOLICITED FINDS
PMID:42637689 · Primary Anastomosis Versus Hartmann's Procedure in Acute Care Surgery: Evidence, Indications, and Barriers to Adoption. · 7/10 PMID:42637240 · Video-Assisted Thoracoscopic Surgery for Empyema Secondary to Upper Gastrointestinal Leakage After Surgical or Endoscopic Intervention: A Multicenter Comparative Study. · 5/10 PMID:42637697 · Early Recurrent Arteriovenous Fistula Stenosis: Identifying Patients Most Likely to Benefit From Drug-Coated Balloon Therapy. · 5/10 PMID:42637699 · The Transfer Advantage: Regional Chest Wall Care Without Delay. · 5/10 PMID:42637700 · Prior Hysterectomy is Associated With Need for Bowel Resection in Women Receiving Surgery for Adhesive Small Bowel Obstruction. · 5/10
📊 TODAY'S BREAKDOWN
- By research category: Early Detection 9 | Treatment Innovation 18 | Public Health 3 | Genomics/Precision Medicine 1 | Diagnostics 5 | Other 2
- By evidence maturity: Exploratory 38
- By watchlist topic: Hematologic malignancies (AML, MDS, CLL, MPN, lymphoma): 15 reviewed / 5 kept / best 7; CBC-based diagnostics and machine learning in hematology: 1 reviewed / 1 kept / best 5; Early cancer detection (liquid biopsy, ctDNA, cfDNA): 10 reviewed / 5 kept / best 7; AI/ML in clinical diagnostics and imaging: 15 reviewed / 5 kept / best 6; Precision oncology and genomic medicine: 15 reviewed / 5 kept / best 6; Novel therapeutics: immunotherapy, CAR-T, targeted therapy: 15 reviewed / 5 kept / best 7; Cardiovascular-metabolic: GLP-1, SGLT2, cardiometabolic risk: 15 reviewed / 3 kept / best 7; Aging, longevity, and population health: 15 reviewed / 1 kept / best 5; Rare diseases with high unmet need: 7 reviewed / 5 kept / best 7
- By source type: peer_reviewed 38 | preprint 0
- Topics with zero 8+ articles this run: Hematologic malignancies (AML, MDS, CLL, MPN, lymphoma); CBC-based diagnostics and machine learning in hematology; Novel therapeutics: immunotherapy, CAR-T, targeted therapy; Aging, longevity, and population health; Rare diseases with high unmet need
🔧 RUN NOTES
- Candidate caps were reached for several high-volume topics; exact truncation and PMID accounting are in Output A.
- All selected PMIDs were fetched in batches of five or fewer and fully accounted for.
- Classification is conservative and based on PubMed citation metadata and abstracts; full text was not reviewed.