Multiplexed EDL-FET biosensor with tannic acid stabilization for simultaneous p-Tau217 and Aβ(42)/Aβ(40) detection in plasma and whole blood from stroke patients.
A blood test accurately identifies early Alzheimer's changes using a protein marker, moving toward simpler screening without brain imaging.
Alzheimer's disease (AD) is a leading cause of disability in aging societies, underscoring the need for practical blood-based biomarker assays. p-tau217 significantly differentiated cognitive status in both matrices, with the strongest performance in plasma.
What the study was
- Study design
- Cohort study
- Population
- patients
- Category
- Public Health
- Maturity
- Exploratory
- Journal
- Analytica chimica acta
Why it surfaced
Score 7/10 [PROMISING_PRELIMINARY]: Cohort study (Journal Article) matched 'Aging, longevity, and population health'. Components — novelty:2/3, relevance:2/3, design:1/2, population:2/2. Confidence: high. Conservative scoring applied per v1.3 rubric.
A plain-language summary of published research — not medical advice. Talk to a clinician about your own care.