Assessing survival in recurrent or metastatic head and neck cancer patients after radiotherapy with/without targeted molecular therapy: A concise systematic review.
This systematic review evaluates the outcomes of different radiotherapeutic strategies in the management of head and neck cancers (HNCs), including curative-intent radiotherapy (RT), palliative stereotactic body radiotherapy (SBRT), multimodal approaches combining surgery and RT Furthermore, the combination of immunotherapy and RT showed potential synergistic effects, improving both OS and progression-free survival (PFS). Furthermore, the combination of immunotherapy and RT showed potential synergistic effects, improving both OS and progression-free survival (PFS).
This systematic review evaluates the outcomes of different radiotherapeutic strategies in the management of head and neck cancers (HNCs), including curative-intent radiotherapy (RT), palliative stereotactic body radiotherapy (SBRT), multimodal approaches combining surgery and RT Furthermore, the combination of immunotherapy and RT showed potential synergistic effects, improving both OS and progression-free survival (PFS). Furthermore, the combination of immunotherapy and RT showed potential synergistic effects, improving both OS and progression-free survival (PFS).
What the study was
- Study design
- Systematic review/meta-analysis
- Sample size
- 26734
- Category
- Treatment Innovation
- Maturity
- Potentially Practice-Changing
- Journal
- Dental and medical problems
Why it surfaced
High-priority Novel therapeutics: immunotherapy, CAR-T, targeted therapy study: promising preliminary signal warrants immediate pipeline escalation.
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