📅 PUBMED DAILY TRIAGE — 2026-09-02 Window: 2026-09-01T09:27:06Z → 2026-09-02T09:27:06Z (CRDT) Topics scanned: 10 | Articles retained: 44 | Candidates evaluated: 110 High priority: 17 | Standard: 27 | Low/archive retained: 0 | Unsolicited finds: 3 Run status: SUCCESS
🔴🟠 HIGH PRIORITY — Best Finds by Topic
Hematologic malignancies
PMID:42679862 · Spleen stiffness measurement rules out high-risk varices in patients with chronic portal vein thrombosis without cirrhosis · 7/10 · Conservative rapid triage: diagnostic validation study, human evidence, and direct relevance to Hematologic malignancies. PMID:42680202 · Enhanced CD33 CAR-NK cells secreting anti-CD73scFv overcome adenosine-mediated immunosuppression and improve anti-AML efficacy · 7/10 · Conservative rapid triage: observational or laboratory study, mixed evidence, and direct relevance to Hematologic malignancies.
CBC-based diagnostics and machine learning in hematology
No high-priority finds today (best candidate scored 7/10).
Early cancer detection
PMID:42677308 · Diagnostic accuracy of cell-free DNA-based non-invasive prenatal testing for fetal aneuploidies: a systematic review · 8/10 · Conservative rapid triage: systematic review, human evidence, and direct relevance to Early cancer detection. PMID:42679926 · Novel insights into Retinoblastoma: From Oncogenic Circuitry to Precision Diagnosis and Eye-Preserving Therapies · 8/10 · Conservative rapid triage: randomized controlled trial, human evidence, and direct relevance to Early cancer detection. PMID:42677123 · Hypoxia-regulated non-coding RNAs in OSCC liquid biopsy: from molecular mechanisms to AI-driven precision oncology · 7/10 · Conservative rapid triage: clinical trial, human evidence, and direct relevance to Early cancer detection. PMID:42679916 · Time-varying prognostic value of circulating tumor DNA in urothelial carcinoma: a systematic review and reconstructed patient-data meta-analysis · 7/10 · Conservative rapid triage: meta-analysis, human evidence, and direct relevance to Early cancer detection. PMID:42676708 · Multi-omic cell free DNA profiles of cerebral spinal fluid from lung cancer metastasis to the brain · 6/10 · Conservative rapid triage: observational or laboratory study, human evidence, and direct relevance to Early cancer detection. PMID:42677377 · Sensitive and Reproducible SERS Profiling of Tumor-Derived EVs via Uniform Microfluidic Nanobowl Arrays for Pancreatic Cancer Management · 6/10 · Conservative rapid triage: diagnostic validation study, mixed evidence, and direct relevance to Early cancer detection. PMID:42678053 · Optimal Positive Control Assays for Methylation-Specific PCR · 6/10 · Conservative rapid triage: observational or laboratory study, unknown evidence, and direct relevance to Early cancer detection. PMID:42679736 · Label- and- enzyme free electrochemical DNA biosensor for ultrasensitive detection of breast cancer prognostic marker ESR1 · 6/10 · Conservative rapid triage: observational or laboratory study, human evidence, and direct relevance to Early cancer detection. PMID:42679775 · Double-end blocker and split input mediated CRISPR-Cas12a system for modular single-base mutation detection with low abundance · 6/10 · Conservative rapid triage: diagnostic validation study, unknown evidence, and direct relevance to Early cancer detection. PMID:42679330 · Relative Mutant Allele Frequency Role in ctDNA-Guided Anti-Epidermal Growth Factor Receptor Rechallenge in Metastatic Colorectal Cancer · 3/10 · Conservative rapid triage: observational or laboratory study, unknown evidence, and direct relevance to Early cancer detection.
AI/ML in clinical diagnostics and imaging
PMID:42680694 · Small Extracellular Vesicle and Total Lipid Profiles Provide a Diagnostic Advantage Over CA-125 Across Ovarian Cancer Subtypes · 6/10 · Conservative rapid triage: cohort study, human evidence, and direct relevance to AI/ML in clinical diagnostics and imaging.
Precision oncology and genomic medicine
PMID:42680631 · International Papillomavirus Society statement on reputed treatments for human papillomavirus infection and human papillomavirus-related diseases: evidence, risks, and standards for clinical evaluation · 7/10 · Conservative rapid triage: systematic review, human evidence, and direct relevance to Precision oncology and genomic medicine. PMID:42679918 · Patient-Derived Organoids for Hepatobiliary Cancers: Molecular Mechanisms, Translational Applications and Precision Therapeutics · 6/10 · Conservative rapid triage: narrative review, human evidence, and direct relevance to Precision oncology and genomic medicine. PMID:42677133 · Advanced nanocatalytic medicine for genitourinary diseases: Reactive oxygen modulation, precision therapeutics, and clinical translation · 5/10 · Conservative rapid triage: preclinical experimental study, in_vitro evidence, and direct relevance to Precision oncology and genomic medicine.
Novel therapeutics
PMID:42680202 · Enhanced CD33 CAR-NK cells secreting anti-CD73scFv overcome adenosine-mediated immunosuppression and improve anti-AML efficacy · 7/10 · Conservative rapid triage: observational or laboratory study, mixed evidence, and direct relevance to Hematologic malignancies. PMID:42680631 · International Papillomavirus Society statement on reputed treatments for human papillomavirus infection and human papillomavirus-related diseases: evidence, risks, and standards for clinical evaluation · 7/10 · Conservative rapid triage: systematic review, human evidence, and direct relevance to Precision oncology and genomic medicine.
Cardiovascular-metabolic
No high-priority finds today (best candidate scored 7/10).
Aging, longevity, and population health
No high-priority finds today (best candidate scored 7/10).
Rare diseases with high unmet need
No high-priority finds today (best candidate scored 0/10).
🟢⚪ STANDARD (5–7) — Top by Topic
Hematologic malignancies
PMID:42680613 · The Prognostic Utility of Normal Karyotype Fraction in Acute Myeloid Leukemia · 7/10 · Treatment Innovation PMID:42679037 · AML1-ETO hijacks a distal enhancer of NAT10 to reprogram glutathione metabolism and sustain leukemia stem cell stemness · 6/10 · Treatment Innovation PMID:42679593 · Haploidentical transplantation versus umbilical cord blood transplantation in acute myeloid leukemia with measurable residual disease · 6/10 · Genomics/Precision Medicine
CBC-based diagnostics and machine learning in hematology
PMID:42675854 · EfficientNet-B0-Based Screening of WBC-Diff Scattergram Images for Hematological Abnormalities · 7/10 · Early Detection
Early cancer detection
PMID:42679155 · Dinuclear Platinum(II) Complexes Targeting DNA and Human Serum Albumin: Electrostatic Binding and Apoptosis-Driven Antiproliferative Activity · 7/10 · Other
AI/ML in clinical diagnostics and imaging
PMID:42680677 · Development and external validation of a contrastive learning foundation model for ECG-based prediction of cardiovascular diseases and outcomes · 7/10 · Diagnostics PMID:42679753 · 3D-FuseNet: An innovative multimodal fusion network for enhancing survival prediction · 6/10 · Diagnostics PMID:42679907 · Cone Beam Computed Tomography-based Lung Function Imaging using Deep Learning for Functional Image-Guided Adaptative Radiation Therapy · 6/10 · Diagnostics PMID:42680190 · Calibrating artificial intelligence against human expertise using femoral nerve segmentation on ultrasound: a consensus framework · 6/10 · Diagnostics
Precision oncology and genomic medicine
PMID:42678714 · Phenotypic and transcriptomic characterization of biallelic RNU2-2 developmental and epileptic encephalopathy · 7/10 · Genomics/Precision Medicine PMID:42677508 · From dysbiosis to precision oncology: translational role of the microbiome in gastrointestinal cancer · 6/10 · Treatment Innovation PMID:42679328 · Establishing a Multicenter Personalized Medicine Program in Childhood, Adolescent, and Young Adult Cancer in Spain: The SEHOP-PENCIL Project · 6/10 · Diagnostics PMID:42680560 · Long-read sequencing reveals widespread novel splicing and neojunction-derived neoantigens in nasopharyngeal carcinoma · 6/10 · Treatment Innovation
Novel therapeutics
PMID:42679859 · New Paradigms in the Management of Castleman Disease · 6/10 · Treatment Innovation PMID:42680071 · Targeting Senescence-Associated Biomarkers: Emerging Strategies for Anti-Ageing Therapy · 6/10 · Treatment Innovation PMID:42680560 · Long-read sequencing reveals widespread novel splicing and neojunction-derived neoantigens in nasopharyngeal carcinoma · 6/10 · Treatment Innovation
Cardiovascular-metabolic
PMID:42679726 · Effects of semaglutide and empagliflozin on markers of endothelial function in persons with type 2 diabetes: A post hoc analysis of a randomized clinical trial · 7/10 · Other PMID:42680068 · Acute Stevia Consumption does not Alter Endocrine Responses in Individuals with Normal Weight, Overweight, and Type 2 Diabetes Mellitus · 7/10 · Other PMID:42679954 · Prescription of medical therapy and postdischarge outcomes in patients hospitalized with HFrEF: insights from the ICARUS registry · 6/10 · Treatment Innovation PMID:42678766 · The Effect of Glucagon-like Peptide-1 Receptor Agonists in Total Joint Arthroplasty: Implications, Complications, and Considerations · 5/10 · Other PMID:42679839 · Ketoacidosis with SGLT2 inhibitors in routine clinical practice of type 2 diabetes: Scandinavian cohort and nested case-control study · 5/10 · Treatment Innovation
Aging, longevity, and population health
PMID:42680254 · A self-selected vegan diet reduces skeletal muscle mass in healthy older adults: a randomized controlled trial · 7/10 · Diagnostics PMID:42680255 · Effect of a PROtein-enriched MEDiterranean diet and EXercise (PROMED-EX) on nutritional status and cognitive performance in older adults at risk of undernutrition and cognitive decline: the PROMED-EX randomized controlled trial · 7/10 · Other PMID:42676999 · Male osteoporosis: pathophysiology, risk assessment, and evidence-based management · 6/10 · Treatment Innovation PMID:42677553 · "Trojan" Methionine Probe Reveals PKM2 as a Methionine-Sensing Protein in the mTORC1 Pathway · 6/10 · Treatment Innovation PMID:42678519 · A population health analysis of trends in lower extremity amputation secondary to diabetes and peripheral artery disease, 2016-2023 · 6/10 · Early Detection
💡 UNSOLICITED FINDS
PMID:42680684 · Impact of Intraoperative Patient-Specific 3D-Printed Temporal Bones: A Randomized Controlled Trial · 6/10 PMID:42680683 · Annular Repair Using an All-Suture Anchor Under Unilateral Biportal Endoscopy: Technical Note and Case Series · 5/10 PMID:42680696 · Genotype-Informed Whole-Animal Kinome Screening Reveals Shared Kinase Vulnerabilities Across Driver Contexts in PDAC · 5/10
📊 TODAY'S BREAKDOWN
- By research category: Diagnostics 8, Early Detection 17, Genomics/Precision Medicine 2, Other 5, Treatment Innovation 12
- By evidence maturity: Exploratory 22, Validated 22
- By watchlist topic:
- Hematologic malignancies: 15 reviewed / 5 kept / highest 7
- CBC-based diagnostics and machine learning in hematology: 1 reviewed / 1 kept / highest 7
- Early cancer detection: 15 reviewed / 11 kept / highest 8
- AI/ML in clinical diagnostics and imaging: 15 reviewed / 5 kept / highest 7
- Precision oncology and genomic medicine: 15 reviewed / 7 kept / highest 7
- Novel therapeutics: 15 reviewed / 5 kept / highest 7
- Cardiovascular-metabolic: 15 reviewed / 5 kept / highest 7
- Aging, longevity, and population health: 15 reviewed / 5 kept / highest 7
- Rare diseases with high unmet need: 0 reviewed / 0 kept / highest 0
- By source type: peer_reviewed 44 | preprint 0
- Topics with zero HIGH-priority articles: CBC-based diagnostics and machine learning in hematology, Cardiovascular-metabolic, Aging, longevity, and population health, Rare diseases with high unmet need
🔧 RUN NOTES
- All selected PMIDs were returned by both ESummary and EFetch; no missing records.
- Topic result sets above their caps were logged as truncated after 15 candidates (10 for sentinel).
- PubMed rejected the requested date sort schema, so its default ordering determined the capped candidate lists.
- Full text was not reviewed; classifications use PubMed abstracts and citation metadata.