📅 PUBMED DAILY TRIAGE — 2026-09-05 Window: 2026-09-04T00:00:00Z → 2026-09-05T09:00:00Z (CRDT) Topics scanned: 10 | Articles retained: 70 | Candidates evaluated: 125 High priority: 26 | Standard: 40 | Low/archive: 4 | Unsolicited finds: 5 Run status: SUCCESS
🔴🟠 HIGH PRIORITY (8+) — Best Finds by Topic
Note: Articles flagged EARLY_CANCER_DETECTION or NOVEL_TREATMENT with score 4–7 also appear in HIGH per schema rules.
Hematologic malignancies
No high-priority finds today (best candidate scored 7/10)
CBC-based diagnostics and ML in hematology
No high-priority finds today (best candidate scored 0/10)
Early cancer detection
- PMID:42696691 · Clinical Relevance of Post-Treatment Circulating Tumor DNA Detection in Early Breast Cance... · 8/10 [EARLY_CANCER_DETECTION] · CONCLUSION: Tissue-free detection of ctDNA 2 years after adjuvant chemotherapy was highly prognostic in an early-stage b...
- PMID:42697086 · Perioperative immunocircadian recovery and its association with circulating tumor DNA-base... · 7/10 [EARLY_CANCER_DETECTION] · CONCLUSION: Distinct perioperative immunocircadian recovery phenotypes were associated with postoperative circulating tu...
- PMID:42696226 · Circulating Biomarkers in Cardio-Oncology: Prediction and Prognostication. · 7/10 [EARLY_CANCER_DETECTION] · FINDINGS: Cardiac troponins and natriuretic peptides remain the most widely studied biomarkers, with troponins demonstra...
- PMID:42696860 · Integrating minimal residual disease into postoperative treatment selection for head and n... · 6/10 [EARLY_CANCER_DETECTION] · Postoperative treatment selection for head and neck squamous cell carcinoma remains largely anchored to static pathologi...
- PMID:42696681 · Deep Learning to Quantify Body Composition in Lung Cancer Screening-Eligible Individuals. · 6/10 [EARLY_CANCER_DETECTION] · CONCLUSION: Automated 3D thoracic BC quantification from LDCT enables opportunistic, artificial intelligence-driven risk...
- PMID:42695880 · Development of a Large-Scale Serum Metabolome Relative Quantitative Method and Application... · 6/10 [EARLY_CANCER_DETECTION] · Colon cancer (CC) is one of the malignant tumors with high incidence and mortality rates worldwide, necessitating innova...
- PMID:42697859 · Multi-Omics Biomarker Signatures for Precision Diagnosis and Prognosis in Primary Liver Ca... · 5/10 [EARLY_CANCER_DETECTION] · Primary liver cancer (PLC) is a biologically heterogeneous group of malignancies dominated by hepatocellular carcinoma (...
- PMID:42697535 · Enhancing Patient Participation in Follow-Up Care for Cervical Cancer Screening Abnormalit... · 5/10 [EARLY_CANCER_DETECTION] · CONCLUSION: The c-HF model improves outreach, scheduling efficiency, and timely follow-up while reducing visit duration.
- PMID:42697163 · Incidence and mortality trends after introduction of lung cancer screening in a community-... · 5/10 [EARLY_CANCER_DETECTION] · CONCLUSION: We observed patterns consistent with a maturing LCS screening program including a non-significant increase i...
- PMID:42696829 · Receipt of Preventive Care and Health Promotion Counseling in Early Stage Breast Cancer Su... · 4/10 [EARLY_CANCER_DETECTION] · CONCLUSIONS: In this cohort of early-stage breast cancer survivors, documented receipt of preventive care was high (>75%...
- PMID:42696090 · A Re-parameterized Network-Based Lightweight Multimodal Fusion Network for Early Lung Canc... · 4/10 [EARLY_CANCER_DETECTION] · Early detection of lung cancer using low-dose computed tomography (LDCT) is critical for improving patient outcomes.
AI/ML in clinical diagnostics and imaging
- PMID:42697307 · PVCuRe: a machine-learning based tool to predict left ventricular systolic function recove... · 8/10 [PROMISING_PRELIMINARY] · CONCLUSION: This ML-based tool, built on widely available variables, accurately estimates the probability of LVEF recove...
- PMID:42697156 · From prediction to reality: Five years of AI in healthcare. Adoption, impact, and the road... · 8/10 [NEAR_TERM_IMPLEMENTABLE] · CONCLUSIONS: The roadmap identified the right domains but misjudged the pace of discontinuous change and overestimated t...
- PMID:42697335 · Targeting the mitochondrial functional network: Decoding upstream pathological mechanisms ... · 6/10 [NOVEL_TREATMENT] · Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder worldwide.
Precision oncology and genomic medicine
- PMID:42694447 · From static risk to dynamic disease monitoring: the role of MRD and immune profiling in mu... · 7/10 [NOVEL_TREATMENT] · The therapeutic landscape of multiple myeloma (MM) has undergone a profound transformation, with highly effective combin...
- PMID:42694519 · Biomarker-guided selection of intravesical therapy in high-risk non-muscle invasive bladde... · 6/10 [EARLY_CANCER_DETECTION] · High-risk non-muscle invasive bladder cancer poses therapeutic challenges, with significant rates of recurrence and prog...
Novel therapeutics (immunotherapy, CAR-T, targeted therapy)
- PMID:42697593 · Evaluating the potential of candidate surrogate endpoints for overall survival in treatmen... · 10/10 [PROMISING_PRELIMINARY] · CONCLUSION: At the individual-level, ORR exhibited a strong correlation with OS, whereas PFS and TNTD showed a moderate ...
- PMID:42697275 · Metastatic patterns, outcomes, and prognostic factors in de novo metastatic head and neck ... · 8/10 [UNDERSERVED_POPULATION] · CONCLUSIONS: cM1 HNSCC has a poor prognosis, highlighting a substantial unmet need.
- PMID:42696863 · Combined emphysema and cancer, from radiology to prognosis in patients treated by immunoth... · 8/10 [PROMISING_PRELIMINARY] · CONCLUSION: In a single-arm cohort of PS2-3 patients with advanced NSCLC treated with 1st-line durvalumab, the presence ...
- PMID:42697609 · The Evolution of Immunotherapy Revolution in Lung Cancer: A 20-Year Perspective. · 6/10 [NOVEL_TREATMENT] · The transition from cytotoxic therapy to the use of treatment to harness the immune system in lung cancer has transforme...
- PMID:42696650 · A Phase 1 Study of PF-07062119, an Anti-GUCY2C/Anti-CD3 Bispecific Fc Antibody, in Patient... · 6/10 [NOVEL_TREATMENT] · CONCLUSIONS: PF-07062119 monotherapy demonstrated a generally tolerable safety profile within the context of this early-...
Cardiovascular-metabolic (GLP-1, SGLT2, cardiometabolic)
- PMID:42697303 · Catheter Ablation of Atrial Arrhythmias After Orthotopic Heart Transplantation. · 8/10 [PROMISING_PRELIMINARY] · Orthotopic heart transplantation (OHT) creates a surgically altered electrophysiologic substrate defined by the suture-l...
Aging, longevity, and population health
- PMID:42696337 · A Novel Moisturizer Formulated With Micronized Centella asiatica and Mandelic Acid Improve... · 9/10 [PROMISING_PRELIMINARY] · CONCLUSION: Twice-daily application of the novel GC skin cream significantly improved the overall skin quality of mature...
Rare diseases with high unmet need
- PMID:42697531 · Conditioning Intensity and Outcomes in Pediatric HLA-Identical Transplant for Sickle Cell ... · 8/10 [UNDERSERVED_POPULATION] · CONCLUSION: NMA conditioning with alemtuzumab and low-dose TBI substantially reduces toxicity compared with MAC and RIC.
- PMID:42697041 · Preclinical evaluation of entecavir as a fetal hemoglobin inducer using in vitro, in vivo,... · 7/10 [NOVEL_TREATMENT] · β-thalassemia is a group of hereditary, autosomal recessive blood disorders caused by reduced synthesis or absence of β-...
- PMID:42696794 · Overcoming access barriers in European CAR-T therapy: the role of decentralized manufactur... · 6/10 [NOVEL_TREATMENT] · CONCLUSIONS: Beyond operational efficiency, the consortium aims to highlight how reduced vein-to-vein time, decentralize...
Sentinel scan (broad high-signal)
No high-priority finds today (best candidate scored 7/10)
🟢⚪ STANDARD (4–7) — Top by Topic
Hematologic malignancies
- PMID:42697852 · Role of direct-acting antivirals in people with HIV-associated non-Hodgkin lymph... · 7/10 · Treatment Innovation
- PMID:42697415 · Long-term adherence to the Mediterranean Diet and risk of rheumatoid arthritis a... · 7/10 · Treatment Innovation
- PMID:42696604 · How I Treat Pediatric Hematology-Oncology Patients from Families Identifying as ... · 7/10 · Treatment Innovation
- PMID:42697801 · Gut Microbiome Composition Is Associated With Response to CD38 Antibody (Daratum... · 6/10 · Treatment Innovation
- PMID:42696806 · Understanding Differences in Resident Loneliness/Isolation Across US Nursing Hom... · 6/10 · Treatment Innovation
AI/ML in clinical diagnostics and imaging
- PMID:42697794 · Digital pathology, image analysis, and artificial intelligence in liver disease. · 7/10 · Diagnostics
- PMID:42697087 · Final thoughts: A value-based vision for safety and quality innovation in surger... · 6/10 · Diagnostics
- PMID:42697496 · Breaking the Autophagy-Oxidative Stress Vicious Cycle in Alzheimer's Disease: La... · 5/10 · Diagnostics
- PMID:42697749 · "Reports in Medical Illustration (REMIL) in Musculoskeletal Radiology: An Evalua... · 4/10 · Diagnostics
- PMID:42697747 · Canadian Medical Students Interested in Radiology Report Greater Perceived Impor... · 4/10 · Diagnostics
Precision oncology and genomic medicine
- PMID:42694252 · A pan-cancer multi-omic SuperLearner for regulated cell death survival topologie... · 7/10 · Genomics/Precision Medicine
- PMID:42695789 · Spectral CT-based Nomogram for Noninvasive Assessment and Prognostic Prediction ... · 6/10 · Genomics/Precision Medicine
- PMID:42695184 · Fatty Acid-Binding Protein 5 Potentially Regulates the Proliferation and Metasta... · 6/10 · Genomics/Precision Medicine
- PMID:42694955 · Targeting Folate Receptors for the Detection and Selective Treatment of Cancer: ... · 6/10 · Genomics/Precision Medicine
- PMID:42694313 · GATES: A Lightweight Tool Automating Pathogenic Variant Discovery From Raw Whole... · 6/10 · Genomics/Precision Medicine
Novel therapeutics (immunotherapy, CAR-T, targeted therapy)
- PMID:42697149 · Assessment of physical activity levels and functional rehabilitation needs in a ... · 6/10 · Treatment Innovation
- PMID:42697131 · Copper complexes Cu1 triggers synergistic immunogenic cell death and pyroptosis ... · 6/10 · Treatment Innovation
- PMID:42697029 · Hyperprogression Upon Cemiplimab Alone or With Short Course Chemotherapy in PD-L... · 6/10 · Treatment Innovation
- PMID:42697001 · Intraoperative and Perioperative Outcomes of Breast-Conserving Surgery After Neo... · 5/10 · Treatment Innovation
- PMID:42696846 · Transforming adoptive macrophages into living immune amplifiers with intracellul... · 5/10 · Treatment Innovation
Cardiovascular-metabolic (GLP-1, SGLT2, cardiometabolic)
- PMID:42697579 · Large-scale multiethnic electronic health record resource for diabetes complicat... · 7/10 · Prevention
- PMID:42697795 · Sex differences in triage priority, predictors, and outcomes in consecutive emer... · 6/10 · Prevention
- PMID:42697752 · Use of fixed-ratio combination of basal insulin and glucagon-like peptide-1 rece... · 6/10 · Prevention
- PMID:42697523 · Body Composition in Heart Failure: A Phenotype-Informed Framework for Assessment... · 6/10 · Prevention
- PMID:42697482 · Historical Gaps in Kidney and Cardiovascular Risk Assessment Among Patients with... · 6/10 · Prevention
Aging, longevity, and population health
- PMID:42697597 · From fortification and foetal surgery to healthy ageing: mentoring leadership th... · 7/10 · Public Health
- PMID:42696642 · Frailty index deficit interchangeability: an empirical test using random surviva... · 6/10 · Public Health
- PMID:42696225 · Sleep disturbances, inflammation, and muscle function in older adults with sarco... · 6/10 · Public Health
- PMID:42695484 · Akkermansia muciniphila and Its Bioactive Derivatives: Emerging Regulators of He... · 6/10 · Public Health
- PMID:42697629 · Bilingual education and cognitive control: An educational neuroscience perspecti... · 5/10 · Public Health
Rare diseases with high unmet need
- PMID:42697517 · Dysregulated phosphatidylglycerol metabolism in dorsal root ganglia contributes ... · 7/10 · Treatment Innovation
- PMID:42697797 · Association between the childhood opportunity index and healthcare utilization i... · 6/10 · Treatment Innovation
- PMID:42697193 · Monoallelic loss-of-function variants in ZNF536 are associated with a neurodevel... · 5/10 · Treatment Innovation
- PMID:42696856 · Postprandial metabolic responses to a glycomacropeptide-based protein substitute... · 5/10 · Treatment Innovation
- PMID:42697798 · Microbial content versus microbial interaction: the impact of medications on CF ... · 4/10 · Treatment Innovation
Sentinel scan (broad high-signal)
- PMID:42696525 · Large Language Models for Heterogeneous Data Mining in Liver Disease: Framework ... · 7/10 · Treatment Innovation
- PMID:42696289 · Designing Social Media Health Warnings for Teenagers and Young Adults: A Randomi... · 7/10 · Other
- PMID:42696283 · Cognitive Behavioral Therapy vs Media Literacy for Prevention of Gaming Disorder... · 7/10 · Treatment Innovation
- PMID:42696155 · Comparison of laparoscopic intraperitoneal onlay mesh (IPOM Plus) and extended t... · 7/10 · Other
- PMID:42693973 · [Effects of external diaphragm pacing on early pulmonary function recovery in in... · 7/10 · Treatment Innovation
🔕 LOW (≤3) — Count Only
- PMID:42696122 · [The role of serological (rapid) tests for the early detection of HPV-... · 3/10 · Abstract retrieved via NCBI efetch
- PMID:42695893 · Phosphoproteomic Profiling of Early-Stage Non-Small Cell Lung Cancer P... · 3/10 · Abstract retrieved via NCBI efetch
- PMID:42696803 · Living at risk and paying the price: The costs of hereditary cancer ca... · 2/10 · Title-only record; score capped at 3
- PMID:42696248 · Postoperative ctDNA in Resectable Gastric Cancer: Prognostically Power... · 2/10 · Title-only record; score capped at 3
💡 UNSOLICITED FINDS (Sentinel Scan)
- PMID:42696525 · Large Language Models for Heterogeneous Data Mining in Liver Disease: Framework Developmen... · 7/10 · Treatment Innovation
- PMID:42696289 · Designing Social Media Health Warnings for Teenagers and Young Adults: A Randomized Clinic... · 7/10 · Other
- PMID:42696283 · Cognitive Behavioral Therapy vs Media Literacy for Prevention of Gaming Disorder and Unspe... · 7/10 · Treatment Innovation
- PMID:42696155 · Comparison of laparoscopic intraperitoneal onlay mesh (IPOM Plus) and extended totally ext... · 7/10 · Other
- PMID:42693973 · [Effects of external diaphragm pacing on early pulmonary function recovery in invasive mec... · 7/10 · Treatment Innovation
📊 TODAY'S BREAKDOWN
- By research category:
- Treatment Innovation: 26
- Early Detection: 15
- Diagnostics: 8
- Genomics/Precision Medicine: 7
- Public Health: 6
- Prevention: 6
- Other: 2
- By evidence maturity:
- Exploratory: 50
- Validated: 20
- By source type: peer_reviewed 70 | preprint 0
- By watchlist topic (reviewed / kept / highest score): ✓ Hematologic malignancies: 15 reviewed / 5 kept / 7/10 highest ✓ CBC-based diagnostics and ML in hematology: 0 reviewed / 0 kept / 0/10 highest ✓ Early cancer detection: 15 reviewed / 11 kept / 8/10 highest ✓ AI/ML in clinical diagnostics and imaging: 15 reviewed / 8 kept / 8/10 highest ✓ Precision oncology and genomic medicine: 14 reviewed / 7 kept / 7/10 highest ✓ Novel therapeutics (immunotherapy, CAR-T, targeted therapy): 14 reviewed / 10 kept / 10/10 highest ✓ Cardiovascular-metabolic (GLP-1, SGLT2, cardiometabolic): 15 reviewed / 6 kept / 8/10 highest ✓ Aging, longevity, and population health: 14 reviewed / 6 kept / 9/10 highest ✓ Rare diseases with high unmet need: 14 reviewed / 8 kept / 8/10 highest ✓ Sentinel scan (broad high-signal): 9 reviewed / 5 kept / 7/10 highest
- Topics with zero HIGH articles today: Hematologic malignancies; CBC-based diagnostics and ML in hematology; Sentinel scan (broad high-signal)
- HIGH flag breakdown:
- EARLY_CANCER_DETECTION: 12
- NOVEL_TREATMENT: 6
- PROMISING_PRELIMINARY: 5
- UNDERSERVED_POPULATION: 2
- NEAR_TERM_IMPLEMENTABLE: 1
🔧 RUN NOTES
- CRDT window: 2026-09-04T00:00:00Z to 2026-09-05T09:00:00Z
- Total topics searched: 10
- T2 (CBC/ML hematology): fallback query used (original = 0 results); fallback also returned 0 — no T2 candidates today
- T10 Sentinel: 10 candidates selected, 9 reviewed; no HIGH-priority finds (best 7/10)
- Conservative caps applied: 4 title-only or score≤3 records downgraded from HIGH→LOW
- Validation gate: 0 errors, 0 warnings; run_status = SUCCESS
- All 70 articles sorted descending by triage_score
- T2: T2 fallback query used; original returned 0 results
- T5: 1 PMIDs already seen in this run (cross-topic dedup)
- T6: 1 PMIDs already seen in this run (cross-topic dedup)
- T8: 1 PMIDs already seen in this run (cross-topic dedup)
- T9: 1 PMIDs already seen in this run (cross-topic dedup)
- T10: 1 PMIDs already seen in this run (cross-topic dedup)