Intravenous lidocaine reduces the propofol EC50 for loss of consciousness and intraoperative anesthetic consumption in gynecological laparoscopy: A randomized controlled trial.
Adding lidocaine before propofol allows doctors to use less anesthetic while maintaining safety during procedures.
BACKGROUND: Intravenous lidocaine reduces propofol requirements and procedure-related adverse events. The concentration was then adjusted in steps of 0.5 μg/mLaccording to Dixon's up-and-down sequential method: decreased if loss of consciousness was achieved, or increased if not.
What the study was
- Study design
- Randomized study
- Population
- patients
- Category
- Other
- Maturity
- Exploratory
- Journal
- Pakistan journal of pharmaceutical sciences
Why it surfaced
Score 7/10 [PROMISING_PRELIMINARY]: Randomized study (Journal Article) matched 'Sentinel'. Components — novelty:1/3, relevance:2/3, design:2/2, population:2/2. Confidence: high. Conservative scoring applied per v1.3 rubric.
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