Daily digest · Fri · 11 Sep 2026

A plain-language summary of published research — not medical advice. Talk to a clinician about your own care.

🔴🟠 HIGH PRIORITY (8+) — Best Finds by Topic

No high-priority finds today.

🟢⚪ STANDARD (5-7) — Top by Topic

42720868 · Trastuzumab Deruxtecan (T-DXd) in HER2-Positive Advanced Gastric and Gastroesophageal Junction Cancer: Evidence, Sequencing, Patient Selection, and Clinical Decision-Making. · 7/10 · Early Detection 42720945 · Management of Soft Tissue and Visceral Leiomyosarcomas. · 7/10 · Genomics/Precision Medicine 42722137 · Tertiary lymphoid structures in pancreatic cancer: molecular mechanisms, heterogeneity, and clinical significance. · 7/10 · Treatment Innovation 42722158 · Second Transplantation for Relapsed Hematologic Malignancies After First Allogeneic Hematopoietic Stem Cell Transplantation From an HLA-Matched Related Donor. · 7/10 · Drug Development 42722166 · B-cell precursor acute lymphoblastic leukaemia: Origins, classification, and therapeutic advances. · 7/10 · Treatment Innovation 42722555 · A Transformer-Based Deep Learning Model for Prediction of Temozolomide Resistance in Glioblastoma Using Pretreatment MRI Images. · 7/10 · Diagnostics 42722598 · Evaluating AI-assisted detection of fetal intracranial malformations in prenatal ultrasound practice: a multicentre, self-crossover, randomised controlled trial in China. · 7/10 · Diagnostics 42720063 · Pretherapeutic radiological sarcopenia in pancreatic ductal adenocarcinoma: a narrative review. · 6/10 · Diagnostics 42720212 · Novel Therapeutic Insights Into Alzheimer's Disease: Glymphatic System and Meningeal Lymphatic Vessels. · 6/10 · Public Health 42720506 · Interpretable four-class machine learning prediction of initial I-131 therapy responses in differentiated thyroid cancer. · 6/10 · Diagnostics 42720514 · Secondary hypoalbuminemia is independently associated with in-hospital mortality in children with Escherichia coli bloodstream infection. · 6/10 · Other 42720808 · Comparative efficacy and safety of fractional carbon dioxide and erbium-based fractional lasers for atrophic acne scars: A systematic review and meta-analysis. · 6/10 · Drug Development 42720875 · Cyclooxygenase-2 selective inhibitors in cancer prevention and therapy: inflammopharmacological basis and translational prospects. · 6/10 · Genomics/Precision Medicine 42721447 · Comparative Analysis of Cardiometabolic Risk Profiles Among Hypertensive and Normotensive Adults: Cross-Sectional Study. · 6/10 · Prevention 42721811 · PI-AttnGAN: Physics-informed attention generative modeling for cross-modal FT-IR-to-Raman serum spectral reconstruction. · 6/10 · Early Detection 42721915 · Tirzepatide and oral progestogens: A hypothesis-generating review of a biologically plausible pharmacokinetic interaction in gynaecologic disease control and menopausal hormone therapy. · 6/10 · Prevention 42722112 · Astrocyte-derived extracellular vesicle phosphorylated TDP-43 as a blood-based biomarker for amyotrophic lateral sclerosis. · 6/10 · Early Detection 42722135 · CAPN1 promotes the progression of MLL-rearranged acute myeloid leukemia by suppressing SHP-1 and activating MAPK/ERK signaling pathway. · 6/10 · Drug Development 42722136 · Targeting skeletal muscle wasting: Emerging therapeutics and translational challenges. · 6/10 · Other 42722199 · Pregnancy as a Window to Future Health: Health Disparities and Social Determinants of Health in Cardiometabolic Risk Across the United States. · 6/10 · Prevention 42722339 · Epidemiologic trends and outcomes of primary vitreoretinal lymphoma in the U.S., 2000-2021. · 6/10 · Drug Development 42722534 · Ultrasound Molecular Imaging and Visualization of Immune Biomarkers: A New Paradigm for Tumor Immunotherapy Response Assessment. · 6/10 · Treatment Innovation 42722554 · Interval Invasive Cancers in Population Screening: A Meta-analysis of Digital Breast Tomosynthesis vs. Digital Mammography. · 6/10 · Early Detection 42720711 · Similarities and Differences Between the Extravascular and the Subcutaneous Implantable Cardioverter-Defibrillator: Clinical Selection and Implantation (Part 1). · 5/10 · Public Health 42721011 · Transcription factor 12 promotes acute myeloid leukemia cell survival by regulating mitochondrial function and ROS. · 5/10 · Drug Development 42721045 · Breast Cancer Screening in Pregnant and Lactating Patients: A Practical Approach. · 5/10 · Early Detection 42721193 · Country- and individual-level factors associated with healthy working life expectancy: A multinational longitudinal study. · 5/10 · Public Health 42721374 · Profiling tumor immune microenvironment of epithelial ovarian carcinoma. · 5/10 · Other 42721959 · Ensemble learning of pathology foundation models for precision oncology. · 5/10 · Treatment Innovation 42722087 · Exercise Snacking for Chronic Conditions and Cardiometabolic Risk: An Evidence Map and Scoping Review. · 5/10 · Prevention 42722239 · Plumieride ameliorates type 2 diabetes and colitis by regulating intestinal functions. · 5/10 · Prevention 42722240 · Metal-Based Epigenetic Therapeutics in Cancer: Mechanisms, Targets, and Opportunities for Overcoming Drug Resistance. · 5/10 · Genomics/Precision Medicine 42722280 · Mast cells suppress glioblastoma progression via endoplasmic reticulum stress. · 5/10 · Treatment Innovation 42722379 · Hypothalamic Inflammaging: A Central Driver of Type 2 Diabetes Mellitus and Metabolic Disease in Aging. · 5/10 · Public Health 42722442 · Tumor-Intrinsic Blood and Imaging Correlatives in Advanced Prostate Cancer Treated with Combination Radiopharmaceutical Therapy and Immunotherapy. · 5/10 · Early Detection

💡 UNSOLICITED FINDS

42720514 · Secondary hypoalbuminemia is independently associated with in-hospital mortality in children with Escherichia coli bloodstream infection. · 6/10 42721374 · Profiling tumor immune microenvironment of epithelial ovarian carcinoma. · 5/10

📊 TODAY'S BREAKDOWN

By research category: {"Early Detection":6,"Genomics/Precision Medicine":3,"Treatment Innovation":5,"Drug Development":5,"Diagnostics":4,"Public Health":4,"Other":3,"Prevention":5}
By evidence maturity: {"Exploratory":35}
By watchlist topic: Hematologic malignancies: 15/5/7; CBC-based diagnostics and machine learning in hematology: 0/0/0; Early cancer detection: 15/6/7; AI/ML in clinical diagnostics and imaging: 15/5/7; Precision oncology and genomic medicine: 11/5/7; Novel therapeutics: 15/6/7; Cardiovascular-metabolic: 14/5/6; Aging, longevity, and population health: 12/4/6; Rare diseases with high unmet need: 1/1/6; Sentinel scan: 10/0/6
By source type: peer_reviewed 35 | preprint 0
Topics with zero 8+ articles this run: Hematologic malignancies, CBC-based diagnostics and machine learning in hematology, Early cancer detection, AI/ML in clinical diagnostics and imaging, Precision oncology and genomic medicine, Novel therapeutics, Cardiovascular-metabolic, Aging, longevity, and population health, Rare diseases with high unmet need, Sentinel scan

🔧 RUN NOTES

24-hour CRDT window; no expansion was needed because at least five relevant records were retained.
Search caps were logged explicitly; no candidate fetches were missing.
PubMed abstracts only; no full text was reviewed.