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‹ Sun · 13 Sep 2026
Promising but preliminary

A therapeutic atlas of monogenic inflammatory bowel disease

Genetic testing can match people with rare inflammatory bowel disease to tailored treatments based on their specific genetic mutations.

Evidence-based, mechanism-guided therapies are urgently needed for treating monogenic inflammatory bowel disease (mIBD). The reported conclusion is: This study highlights the potential of precision medicine approaches tailored to genetic and pathway-specific mechanisms, while underscoring the urgent need for effective therapies in many monogenic conditions that remain without established treatment options.

What the study was

Study design
Systematic review
Category
Genomics/Precision Medicine
Maturity
Exploratory
Journal
Journal of Crohn's & colitis

Why it surfaced

Retained for Precision oncology and genomic medicine; score reflects the available PubMed abstract, study design, clinical relevance, and unmet need.

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