📅 PUBMED DAILY TRIAGE — 2026-09-14 Window: 2026-09-13T00:00:00Z → 2026-09-14T09:21:44Z (CRDT) Topics scanned: 10 | Articles reviewed: 88 | Candidates evaluated: 88 High priority: 16 | Standard: 59 | Low/archive: 1 | Unsolicited finds: 7 Run status: SUCCESS
🔴🟠 HIGH PRIORITY (8+) — Best Finds by Topic
Hematologic malignancies (AML, MDS, CLL, MPN, lymphoma)
[PMID42732301] · Efficacy and safety of daratumumab-based quadruplet therapy vs non-daratumumab-based triplet therapy · 9/10 · In conclusion, adding daratumumab to standard frontline treatment improves outcomes in newly diagnosed multiple myeloma,
Rare diseases with high unmet need
[PMID42732416] · Intestinal Lymphangioma With Extensive Secondary Lymphangiectasia Causing Life-Threatening Hemorrhag · 9/10 · The atypical presentation without classic protein-losing enteropathy features, multiorgan gastrointestinal involvement, [PMID42732287] · Telitacicept for primary angiitis of the central nervous system: A real-world retrospective study. · 8/10 · Larger studies are needed to confirm its benefits and long-term safety.
Early cancer detection (liquid biopsy, ctDNA, cfDNA)
[PMID42732946] · Comprehensive In Silico Analysis Identifies MSTO1 and LIG1 as Candidate Biomarkers With Diagnostic a · 8/10 · Their differential expression and functional essentiality in HCC cell lines highlighted their value for further experime [PMID42732081] · Molecular events underlying sarcoma development and progression: the diagnostic relevance. · 8/10 · There is an ongoing need for further studies aimed to uncover the complete mechanisms behind the development and progres [PMID42732249] · Artificial Intelligence as an Assistive Tool in Breast Cancer Screening and Diagnosis in the Digital · 7/10 · The use of AI in the analysis of pathological samples in diagnosis, research, precision medicine, and patient care is in [PMID42732145] · Genotoxicity effects in Cancer Patients: Evaluation by Micronucleus and Comet Assays and Correlatio · 6/10 · Alterations in the blood and biochemical parameters further support the systemic effects of malignancy. [PMID42732107] · Gaps in Knowledge and Practice of Cervical Cancer Screening among Primary Health Care Workers in Lag · 6/10 · These findings highlight the need for policy interventions aimed at strengthening primary health care systems in Nigeria [PMID42732708] · Cervical cancer screening in Sub-Saharan Africa: A scoping review of test and treat and test, triage · 5/10 · These approaches are essential to improve coverage, reduce attrition and support sustainable progress towards cervical c
Precision oncology and genomic medicine
[PMID42732946] · Comprehensive In Silico Analysis Identifies MSTO1 and LIG1 as Candidate Biomarkers With Diagnostic a · 8/10 · Their differential expression and functional essentiality in HCC cell lines highlighted their value for further experime [PMID42732787] · Targeting intracellular immune regulatory molecules for cancer immunotherapy in solid tumors. · 8/10 · Among these targets, HPK1 inhibitors have demonstrated preliminary monotherapy activity in selected patients, whereas th [PMID42732249] · Artificial Intelligence as an Assistive Tool in Breast Cancer Screening and Diagnosis in the Digital · 7/10 · The use of AI in the analysis of pathological samples in diagnosis, research, precision medicine, and patient care is in [PMID42732768] · Integrated Analysis of HER2 Expression and ERBB2 Alterations in Bladder Cancer. · 6/10 · Their integrated assessment may improve molecular stratification and guide future biomarker-driven studies.
Novel therapeutics: immunotherapy, CAR-T, targeted therapy
[PMID42732787] · Targeting intracellular immune regulatory molecules for cancer immunotherapy in solid tumors. · 8/10 · Among these targets, HPK1 inhibitors have demonstrated preliminary monotherapy activity in selected patients, whereas th [PMID42732768] · Integrated Analysis of HER2 Expression and ERBB2 Alterations in Bladder Cancer. · 6/10 · Their integrated assessment may improve molecular stratification and guide future biomarker-driven studies.
AI/ML in clinical diagnostics and imaging
[PMID42732249] · Artificial Intelligence as an Assistive Tool in Breast Cancer Screening and Diagnosis in the Digital · 7/10 · The use of AI in the analysis of pathological samples in diagnosis, research, precision medicine, and patient care is in
CBC-based diagnostics and machine learning in hematology
No high-priority finds today (best candidate scored 0/10)
Cardiovascular-metabolic: GLP-1, SGLT2, cardiometabolic risk
No high-priority finds today (best candidate scored 7/10)
Aging, longevity, and population health
No high-priority finds today (best candidate scored 6/10)
🟢⚪ STANDARD (5-7) — Top by Topic
Early cancer detection (liquid biopsy, ctDNA, cfDNA)
[PMID42732841] · Optimizing deep learning-enhanced opportunistic osteoporosis screening from chest X-rays in Australi · 7/10 · Early Detection [PMID42732490] · Nipah virus in the era of global connectivity: molecular evolution, transmission risk, and preparedn · 7/10 · Early Detection [PMID42732540] · [Current management of thyroid cancer in Hungary]. · 6/10 · Early Detection [PMID42732825] · Musculoskeletal Assessment of Forelimbs and Hindlimbs in Mounted Police Horses using Infrared Thermo · 5/10 · Early Detection [PMID42732688] · Machine learning-assisted optimization of a BK7/Ag/As₂S₃/graphene surface plasmon resonance biosenso · 5/10 · Diagnostics
AI/ML in clinical diagnostics and imaging
[PMID42732713] · Multimodal artificial intelligence-based decision support for stroke classification in medical emerg · 7/10 · Diagnostics [PMID42732586] · Diagnostic Potential of Artificial Intelligence for Detecting Vertical Root Fractures on Dental Imag · 7/10 · Diagnostics [PMID42732219] · Artificial intelligence-based multimodal integration of ultrasound and digital breast tomosynthesis · 7/10 · Diagnostics [PMID42732587] · Artificial Intelligence for Detection and Prevention of Separated Endodontic Instruments: A Scoping · 6/10 · Diagnostics [PMID42732741] · Radiomics and dosiomics in radionecrosis prediction in brain metastasis treated with Stereotactic Ra · 5/10 · Treatment Innovation
Precision oncology and genomic medicine
[PMID42732678] · Inflammation biomarkers in cancer: mechanistic drivers, diagnostic innovations, and future clinical · 7/10 · Treatment Innovation [PMID42732218] · miRNA-34a-5p is a novel biomarker and modulator of the radioresponse in esophageal adenocarcinoma. · 7/10 · Treatment Innovation [PMID42732528] · Longitudinal plasma neurofilament light chain and patient-reported outcomes as complementary markers · 6/10 · Treatment Innovation [PMID42732535] · Research Progress on Hemoglobin Expression in Non-Erythroid Cells and Tumor Cells. · 6/10 · Treatment Innovation [PMID42732333] · Microbial Signals in Cancer: Dissecting Host-Microbiota-Tumor Interactions and Potential Therapeutic · 6/10 · Treatment Innovation
Cardiovascular-metabolic: GLP-1, SGLT2, cardiometabolic risk
[PMID42732789] · Operational definitions of type 2 diabetes influence study population characteristics and outcome as · 7/10 · Diagnostics [PMID42732703] · Cardiovascular risk estimation using the steno type 1 risk engine in Brazilian individuals with type · 7/10 · Treatment Innovation [PMID42732446] · Cardiometabolic Outcomes and Levothyroxine Treatment Effects in Subclinical Hypothyroidism: A System · 7/10 · Treatment Innovation [PMID42732387] · Association Between the Atherogenic Index of Plasma and the Occurrence of Slow Flow/No-Reflow in Pat · 7/10 · Diagnostics [PMID42732142] · What is the impact of metabolic dysfunction-associated steatotic liver disease (MASLD) on outcomes i · 7/10 · Treatment Innovation
Hematologic malignancies (AML, MDS, CLL, MPN, lymphoma)
[PMID42733002] · Resistance mechanisms and therapeutic strategies after menin inhibitor failure in acute myeloid leuk · 6/10 · Treatment Innovation [PMID42732528] · Longitudinal plasma neurofilament light chain and patient-reported outcomes as complementary markers · 6/10 · Treatment Innovation [PMID42732150] · Baseline Extracellular HMGB-1 Levels Associated with Induction Chemotherapy Response in Adult Acute · 6/10 · Treatment Innovation [PMID42732478] · Adverse events, quality of life, and work impairment in patients with chronic myeloid leukemia (CML) · 5/10 · Diagnostics [PMID42732189] · Impulse Control Disorders Are Independent of Parkinson Disease Motor Subtypes. · 5/10 · Diagnostics
Novel therapeutics: immunotherapy, CAR-T, targeted therapy
[PMID42732333] · Microbial Signals in Cancer: Dissecting Host-Microbiota-Tumor Interactions and Potential Therapeutic · 6/10 · Treatment Innovation [PMID42732951] · Multi-pool Model-based Amide Proton Transfer Imaging for Tumor Characterization and Risk Stratificat · 6/10 · Diagnostics [PMID42732673] · Engineering next-generation CAR-T cells for glioblastoma treatment: a review of innovations in recep · 6/10 · Treatment Innovation [PMID42732672] · Multi-omics and spatial transcriptomics reveal that S100A10 drives CD8+ T-cell exhaustion and immune · 6/10 · Treatment Innovation [PMID42732660] · Acrylamide-associated gastric cancer progression involves RRM2-related nucleotide metabolic dysregul · 6/10 · Treatment Innovation
Aging, longevity, and population health
[PMID42732921] · A Review of Senescence-Associated Secretory Phenotype-Mediated Remodeling of the Tumor Microenvironm · 6/10 · Treatment Innovation
Rare diseases with high unmet need
[PMID42732210] · Pancreatitis and Myocardial Infarction as Complications of Thrombotic Thrombocytopenic Purpura: A Ca · 4/10 · Early Detection
💡 UNSOLICITED FINDS
[PMID42732874] · Adjuvant Osimertinib in Resected EGFR-Mutated Stage IB-IIIA Non-Small Cell Lung Cancer: Exploratory · 9/10 [PMID42733004] · A rapid systematic review of palliative uses of ketamine for depression and pain in people living wi · 8/10 [PMID42732888] · Breast cancer overdiagnosis in mammography trials-separating signal from noise: a meta-analysis. · 8/10 [PMID42732820] · Patient-clinician symptom agreement before and after radiotherapy for prostate cancer: results from · 8/10 [PMID42732599] · [Effect of sulodexide on the walking, erectile and cognitive functions based on the findings of the · 8/10
📊 TODAY'S BREAKDOWN
- By research category: Diagnostics: 26, Early Detection: 10, Genomics/Precision Medicine: 1, Other: 1, Prevention: 1, Treatment Innovation: 37
- By evidence maturity: Exploratory: 48, Potentially Practice-Changing: 11, Validated: 17
- By watchlist topic: Hematologic malignancies (AML, MDS, CLL, MPN, lymphoma): reviewed=8, high=1, best_score=9 CBC-based diagnostics and machine learning in hematology: reviewed=0, high=0, best_score=0 Early cancer detection (liquid biopsy, ctDNA, cfDNA): reviewed=15, high=2, best_score=8 AI/ML in clinical diagnostics and imaging: reviewed=6, high=0, best_score=7 Precision oncology and genomic medicine: reviewed=15, high=2, best_score=8 Novel therapeutics: immunotherapy, CAR-T, targeted therapy: reviewed=15, high=1, best_score=8 Cardiovascular-metabolic: GLP-1, SGLT2, cardiometabolic risk: reviewed=15, high=0, best_score=7 Aging, longevity, and population health: reviewed=1, high=0, best_score=6 Rare diseases with high unmet need: reviewed=3, high=2, best_score=9 Sentinel scan: reviewed=10, high=5, best_score=9
- By source type: peer_reviewed 75 | preprint 1
- Topics with zero 8+ articles this run: CBC-based diagnostics and machine learning in hematology, AI/ML in clinical diagnostics and imaging, Cardiovascular-metabolic: GLP-1, SGLT2, cardiometabolic risk, Aging, longevity, and population health
🔧 RUN NOTES
- CBC-based diagnostics and machine learning in hematology: primary query returned 0 results; used fallback query.