Pulse.

a daily field guide to health research that matters

◆ Console

‹ Wed · 16 Sep 2026
Promising but preliminary

Chidamide plus venetoclax as effective and safe maintenance therapy in high-risk acute myeloid leukemia and myelodysplastic syndrome post-transplantation.

Relapse after allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains the leading cause of treatment failure in high-risk acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS), yet effective maintenance strategies are currently lacking. The combination of chidamide (CHI) and venetoclax (VEN) represents a novel approach.

Relapse after allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains the leading cause of treatment failure in high-risk acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS), yet effective maintenance strategies are currently lacking. The combination of chidamide (CHI) and venetoclax (VEN) represents a novel approach.

What the study was

Study design
Journal Article (unspecified)
Category
Treatment Innovation
Maturity
Exploratory
Journal
Ann Hematol

Why it surfaced

Matched watchlist topic 'Hematologic malignancies (AML, MDS, CLL, MPN, lymphoma)'. Study design: Journal Article (unspecified). Score: 8/10 (N:3, R:3, D:1, P:1).

A plain-language summary of published research — not medical advice. Talk to a clinician about your own care.