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‹ Mon · 21 Sep 2026
Early cancer detection or prevention

ctDNA in the Management of Resectable & Advanced Colorectal Cancer: Current Status and Future Directions.

Circulating tumor DNA shows promise for predicting colorectal cancer outcomes, though its clinical value in decision-making remains uncertain.

This review summarizes circulating tumor DNA evidence across resectable and advanced colorectal cancer. It supports prognostic use while emphasizing that clinical utility and outcome benefit remain incompletely proven.

What the study was

Study design
Structured narrative review
Population
Patients with resectable or advanced colorectal cancer
Category
Early Detection
Maturity
Exploratory
Journal
OncoTargets and therapy

Why it surfaced

The article is highly relevant to liquid-biopsy surveillance and carefully separates prognostic validity from proven clinical utility, but it is a review rather than new prospective evidence.

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