Precision oncology in GI-cancers: Mechanisms of action, indications and ongoing strategies to overcome primary and secondary resistance.
Targeted therapies address specific mutations in gastrointestinal cancers, refining treatment options for patients with detected alterations.
This review summarizes targeted therapies for recurrent actionable alterations across gastrointestinal cancers. It is highly relevant to precision oncology but does not contribute new comparative clinical evidence.
What the study was
- Study design
- Narrative review of precision-oncology mechanisms and clinical evidence
- Population
- Patients with gastrointestinal cancers and actionable molecular alterations
- Category
- Genomics/Precision Medicine
- Maturity
- Exploratory
- Journal
- Seminars in cancer biology
Why it surfaced
The article is a current and clinically relevant treatment map, but its evidence contribution is synthetic rather than primary.
A plain-language summary of published research — not medical advice. Talk to a clinician about your own care.