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‹ Tue · 22 Sep 2026
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Contemporary Treatment and Survival Outcomes in Mantle Cell Lymphoma: A National Real-World Analysis From REALYSA, a LYSA Cohort

Real-world outcomes in mantle cell lymphoma patients show how newer therapies are translating into improved survival outside of controlled clinical trials.

Using the prospective REALYSA registry, this study characterized contemporary treatment and survival outcomes in MCL patients treated outside of clinical trials. The analysis highlights how evolving therapies translate into real-world practice in this aggressive B-cell lymphoma.

What the study was

Study design
Prospective cohort / Real-world registry (REALYSA)
Population
Adults with mantle cell lymphoma
Category
Treatment Innovation
Maturity
Validated
Journal
Hematological oncology

Why it surfaced

Large real-world prospective registry data on MCL outcomes; bridges clinical trial efficacy and real-world practice for a high-unmet-need lymphoma.

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