Managing IBS-Like Symptoms in Quiescent Inflammatory Bowel Disease: A Meta-Analysis of Randomized Trials.
Dietary approaches may help ease stubborn digestive symptoms in IBD patients whose inflammation is controlled, addressing a common unmet need.
BACKGROUND AND AIMS: Persistent IBS-like symptoms affect up to one-third of patients with inflammatory bowel disease (IBD) in remission, representing a major unmet need not addressed by anti-inflammatory therapies. Dietary interventions demonstrated the largest pooled symptom benefit (SMD -1.33, 95% CI -4.42 to 1.77; I2=90%), although evidence was very low certainty because of heterogeneity and imprecision.
What the study was
- Study design
- Randomized study
- Population
- patients
- Sample size
- 688
- Category
- Genomics/Precision Medicine
- Maturity
- Exploratory
- Journal
- Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
Why it surfaced
Score 7/10 [PROMISING_PRELIMINARY]: Randomized study (Journal Article) matched 'Rare diseases with high unmet need'. Components — novelty:1/3, relevance:2/3, design:2/2, population:2/2. Confidence: high. Conservative scoring applied per v1.3 rubric.
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